4-Aminosalicylic acid (CAS 65-49-6) selection notes

2026-10-17 · Keyword：4-Aminosalicylic acid · CAS 65-49-6 · Jinan Shenghe Chemical Co., Ltd. · 中文

4-Aminosalicylic acid (CAS 65-49-6) isn't a load-and-go material. In Cosmetic & Personal-Care Raw Materials, the dosing rhythm and how it meshes with the rest of the system usually decide the final result, so this page unpacks those parts.

Let's get the mechanism first

Its role in one sentence:

In Cosmetic & Personal-Care Raw Materials, 4-Aminosalicylic acid (CAS 65-49-6) must clear the safety-and-compliance bar before any talk of feel, stability or performance. Such ingredients face compatibility issues with pH, ionic strength and the preservative system, and a small formulation tweak can change clarity, precipitation or irritation risk. So regulatory status and impurity profile are usually reviewed before the assay figure. Comparable grades:

2,6-Dimethoxyphenol (CAS 91-10-1)：a comparable grade often evaluated alongside。
Methyl phenethyl ether (CAS 3558-60-9)：a comparable grade often evaluated alongside。
Rotundone (CAS 14765-30-1)：a comparable grade often evaluated alongside。
Ammonium bromide (CAS 12124-97-9)：a comparable grade often evaluated alongside。
Acetylsalicylic acid (CAS 50-78-2)：a comparable grade often evaluated alongside。
Aluminium stearate (CAS 637-12-7)：a comparable grade often evaluated alongside。
Acetic acid,sodium salt trihydrate (CAS 6131-90-4)：a comparable grade often evaluated alongside。
Albuterol sulfate (CAS 51022-70-9)：a comparable grade often evaluated alongside。

Thinking through the choice

The one I weigh most: Confirm regulatory status first (INCI name, restricted concentration, toxicology / safety assessment) to avoid a material limited in your target market.

Watch heavy metals, microbes and residual solvents, and compatibility with your existing preservative system.

Run stability (heat / cold / light) and compatibility trials before scaling; confirm no precipitation, separation or irritation.

Retain samples and request COA / toxicology summary, with third-party retest where needed.

Its typical specs: name 4-Aminosalicylic acid, CAS 65-49-6, formula C7H7NO3, MW 153.14 g/mol, standard purity per batch COA, packaging confirmed per order, storage keep sealed in a cool, dry place. Final values follow the batch COA and order confirmation.

Where most cases go wrong

Comparing assay only, ignoring safety indicators: cosmetics are more sensitive to heavy metals, microbes and sensitising impurities — passing assay does not mean usable.

Skipping regulatory checks and going straight to formula: some substances are restricted by concentration or use in different markets, causing whole-batch rework.

Scaling without stability tests: a shift in pH or ionic strength can precipitate or separate, often invisible at the bench stage.

Things we get asked a lot

What does 4-Aminosalicylic acid do in Cosmetic & Personal-Care Raw Materials?

As a functional or auxiliary raw material it influences feel, stability or system compatibility; the exact role depends on the overall formula and addition level.

Which compliance documents should I confirm when sourcing 4-Aminosalicylic acid?

Focus on INCI name, restricted concentration, toxicology / safety assessment and batch COA; cross-border or specific markets need corresponding regulatory clearance files.

Can these materials be used directly in finished cosmetics?

Products here are supplied for industrial and research use. Cosmetic use requires a finished-formula safety assessment and regulatory clearance per target market.

Related products worth a look

See site search for 4-Aminosalicylic acid or browse the Organic Chemicals directory.

Procurement contact

Jinan Shenghe Chemical Co., Ltd. supplies chemical raw materials and fine chemicals; a COA ships with every batch, with MSDS and technical data sheets available on request. In your enquiry include product name, CAS, target purity and packaging, and we will provide documents and a quote to the relevant standard.

Contact: info@591daili.com | +86-18553102138

Note: This page is for industrial raw-material technical discussion only. Products are supplied for industrial and research use, not for consumer or medical use. Drinking-water, food, cosmetic or pharmaceutical applications must meet applicable regulations and customer standards; specifications, compliance documents and transport requirements follow the batch COA and order confirmation.