1,1,1,2,3,3,3-Heptafluoropropane

Description

1,1,1,2,3,3,3-Heptafluoropropane · CAS 431-89-0 · C3HF7. UNII R40P36GDK6. Boiling Point: -16.34 °C; Melting Point: -126.8 °C; Density: 1.394 g/cu cm at 25 °C.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Liquid
• Liquefied gas; [MSDSonline]
• Colorless gas
• Light ethereal odor
• Critical density: 0.582 g/cu cm; heat of evaporation: 208.96 kJ/kg at BP
• Vapor pressure (kPa): 86.7 at -20 °C; 196.2 at 0 °C; 390.2 at 20 °C; 702.9 at 40 °C; 1174.7 at 60 °C; 1857.2 at 80 °C; 2824.6 at 100 °C

Regulatory Status

GHS Hazard Classification

Documented Uses

• ... HFC 227ea can be used as ... /a propellant/ in medicinal aerosols instead of CFC 114.
• HFC 227ea is being developed as a CFC replacement in refrigerants, high temperature heat pumps, air-conditioning systems; as a fire suppressant; and for pharmaceutical aerosols and metered-dose inhalers.
• Propellants for medical sprays including: MDIs (Metered Dose Inhalers) also known as pharmaceutical aerosols or asthma sprays for the treatment of asthma, COPD (Chronic Obstructive Pulmonary Disorder) and respiratory infections; nasal sprays for the treatment of allergic rhinitis; foam sprays; oral and topical sprays (e.g. nerve sensitization, tooth vitality, pain relaxation).
• Propellants, non-motive (blowing agents)
• Monohydroperfluoroalkanes can be obtained by adding hydrogen fluoride to perfluoroalkenes (e.g., CF3-CHF-CF3, HFC 227ea) or by decarboxylation of perfluorocarboxylates in the presence of proton donors.
• 2023: 2,500,000 - <4,000,000 lb

Synonyms

1,1,1,2,3,3,3-Heptafluoropropane; 431-89-0; Apaflurane; 2H-Heptafluoropropane; HFC-227ea; Solkane 227; 2-Hydroheptafluoropropane; HFA-227; Propane, 1,1,1,2,3,3,3-heptafluoro-; Khladon 227; HFC-227; 2-Hydroperfluoropropane; HFC 227; Apaflurano; FM 200; HFA-227EA

Frequently Asked Questions

What are the CAS number and molecular formula of 1,1,1,2,3,3,3-Heptafluoropropane?

CAS 431-89-0; molecular formula C3HF7; molecular weight — g/mol.

What other names is 1,1,1,2,3,3,3-Heptafluoropropane known by?

1,1,1,2,3,3,3-Heptafluoropropane, 431-89-0, Apaflurane, 2H-Heptafluoropropane, HFC-227ea, Solkane 227.

Is 1,1,1,2,3,3,3-Heptafluoropropane classified as hazardous?

8.6% of GHS notifications report no hazard classification (24 of 279).

What are the key physical properties of 1,1,1,2,3,3,3-Heptafluoropropane?

Boiling Point: -16.34 °C; Melting Point: -126.8 °C; Density: 1.394 g/cu cm at 25 °C; Vapor Density: 4.2 at 20 °C (Air = 1).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.