2'-Chloroacetanilide

Description

2'-Chloroacetanilide · CAS 533-17-5 · C8H8ClNO. UNII 20C42PA69Y. Melting Point: 88 °C; Vapor Pressure: 0.0000963 [mmHg]; LogP: 1.35.

Identification

CAS Registry Number	533-17-5
PubChem CID	10777
Molecular formula	C8H8ClNO
IUPAC name	N-(2-chlorophenyl)acetamide
UNII (FDA)	20C42PA69Y

Computed Descriptors

Molecular Weight	169.61
XLogP3	1.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Exact Mass	169.0294416
Monoisotopic Mass	169.0294416
Topological Polar Surface Area	29.1
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

Melting Point	88 °C
Vapor Pressure	0.0000963 [mmHg]
LogP	1.35
Other Experimental Properties	SUBLIMES AT ABOUT 50-60 °C

Physical description & handling notes

• Solid; [HSDB] Brown crystalline powder; [Alfa Aesar MSDS]
• NEEDLES FROM DIL ACETIC ACID
• PRACTICALLY INSOL IN WATER, ALKALIES; SOL IN ALCOHOL
• MORE SOL IN BENZENE THAN P-CHLOROACETANILIDE
• VERY SOL IN ETHER, HOT BENZENE
• INDEX OF REFRACTION (95% ETHANOL): 240 NM (LOG E= 4.02)

GHS Hazard Classification

Reported hazard statements	H315 (100%), H319 (100%), H335 (97.7%)

Documented Uses

• Used as chemical intermediate; [HSDB]
• ...FROM O-CHLOROANILINE & ACETIC ANHYDRIDE: ROBERTS ET AL, J ORG CHEM 24: 654 (1959). COMMERCIAL PREPN: ANDERSON; YOUNG, BARBARO, US PATENTS 2,617,794 & 2,691,010; 2,708,667 (1952, 1954, & 1955, ALL TO AM CYANAMID).
• Acetamide, N-(2-chlorophenyl)-: ACTIVE
• SUBLIMES AT ABOUT 50-60 °C, & CAN BE REMOVED FROM MIXTURE WITH CORRESPONDING P-ISOMER IN THIS MANNER...
• YIELDS O-CHLOROANILINE IN THE RAT. BRAY HG ET AL; BIOCHEM J 47: 483 (1950). /FROM TABLE/

Synonyms

2'-Chloroacetanilide; N-(2-Chlorophenyl)acetamide; O-CHLOROACETANILIDE; Acetamide, N-(2-chlorophenyl)-; 2'-Chloro acetanilide; UNII-20C42PA69Y; HSDB 1408; 20C42PA69Y; NSC-8455; EINECS 208-555-2; NSC 40562; NSC-40562; Acetic acid, amide, N-(2-chlorophenyl)-; ACETANILIDE, O-CHLORO-; DTXSID2060200; KNVQTRVKSOEHPU-UHFFFAOYSA-

Frequently Asked Questions

What are the CAS number and molecular formula of 2'-Chloroacetanilide?

CAS 533-17-5; molecular formula C8H8ClNO; molecular weight — g/mol.

What other names is 2'-Chloroacetanilide known by?

2'-Chloroacetanilide, N-(2-Chlorophenyl)acetamide, O-CHLOROACETANILIDE, Acetamide, N-(2-chlorophenyl)-, 2'-Chloro acetanilide, UNII-20C42PA69Y.

Is 2'-Chloroacetanilide classified as hazardous?

Hazard statements reported: H315, H319, H335.

What are the key physical properties of 2'-Chloroacetanilide?

Melting Point: 88 °C; Vapor Pressure: 0.0000963 [mmHg]; LogP: 1.35; Other Experimental Properties: SUBLIMES AT ABOUT 50-60 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.