3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone

Description

3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone · CAS 77439-76-0 · C5H3Cl3O3. UNII SSD7YR4366.

Identification

Computed Descriptors

GHS Hazard Classification

Documented Uses

• 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) is not known to be produced commercially except for research purposes.
• Disinfection byproducts are formed when disinfectants used in water treatment plants react with bromide and/or natural organic matter (i.e., decaying vegetation) present in the source water. /Disinfection byproducts/
• In acidic solutions MX is a furanone, but at physiological pH it exists primarily in a ring-open form, namely Z-2-chloro-3-(dichloromethyl)-4-oxo-butenoic acid (z-MX), a fraction of which undergoes isomerization to its geometric isomer (E)-2-chloro-3-(dichloromethyl)-4-oxobutenoic acid (EMX).
• Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
• Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.
• In another experiment, a dose of 2 mg/kg (14C)MX was administered to Wistar rats and radioactivity was determined in tissues after 2 and 6 hr. After 2 hr, the highest amount of radioactivity was detected in kidneys, followed by the stomach, ileum, urinary bladder and liver. At 6 hr, the concentration of radioactivity was markedly decreased in kidneys and urinary bladder and to a lesser extent in the gastrointestinal tract.

Synonyms

3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone; 77439-76-0; Mutagen X; MX mutagen; 3-DCHFO; DTXSID6020276; Chloro(dichloromethyl)-5-hydroxy-2(5H)-furanone; 3-Chloro-4-dichloromethyl-5-hydroxy-2-furanone; SSD7YR4366; DTXCID40276; RefChem:499908; 3-chloro-4-(dichloromethyl)-5-hydroxyfuran-2(5H)-one; 4-chloro-3-(dichloromethyl)-2-hydroxy-2H-furan-5-one; 3-Chloro-4-dichloromethyl-5-hydroxy-2(5H)-furanone; 2(5H)-Furanone, 3-chloro-4-dichloromethyl-5-hydroxy-; 3-chloro-4-(dichloromethyl)-5-hydroxy-2,5-dihydrofuran-2-one

Frequently Asked Questions

What are the CAS number and molecular formula of 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone?

CAS 77439-76-0; molecular formula C5H3Cl3O3; molecular weight — g/mol.

What other names is 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone known by?

3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone, 77439-76-0, Mutagen X, MX mutagen, 3-DCHFO, DTXSID6020276.

Is 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone classified as hazardous?

Hazard statements reported: H301, H310, H351, H370.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.