3'-chloroacetanilide

Description

3'-chloroacetanilide · CAS 588-07-8 · C8H8ClNO. UNII 74H09HU61J. Melting Point: 77-78 °C; Vapor Pressure: 0.0000963 [mmHg]; LogP: 2.02.

Identification

CAS Registry Number	588-07-8
PubChem CID	11493
Molecular formula	C8H8ClNO
IUPAC name	N-(3-chlorophenyl)acetamide
UNII (FDA)	74H09HU61J

Computed Descriptors

Molecular Weight	169.61
XLogP3	2.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Exact Mass	169.0294416
Monoisotopic Mass	169.0294416
Topological Polar Surface Area	29.1
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

Melting Point	77-78 °C
Vapor Pressure	0.0000963 [mmHg]
LogP	2.02

Physical description & handling notes

• Solid; [HSDB] Off-white or beige granules; [Alfa Aesar MSDS]
• NEEDLES FROM 50% GLACIAL ACETIC ACID
• READILY SOL IN ALC, BENZENE, CARBON DISULFIDE; VERY SLIGHTLY SOL IN PETROLEUM ETHER
• SLIGHTLY SOL IN WATER

GHS Hazard Classification

Reported hazard statements	H315 (100%), H319 (100%), H335 (97.7%)

Documented Uses

• Used to make pharmaceuticals; [HSDB]
• REACTION OF M-CHLOROANILINE AND ACETIC ANHYDRIDE
• Acetamide, N-(3-chlorophenyl)-: INACTIVE
• YIELDS 4-ACETAMIDO-2-CHLOROPHENOL IN RABBIT: DALY ET AL, BIOCHEM PHARMAC, 17, 31 (1968); M-CHLOROANILINE IN RAT: BRAY ET AL, BIOCHEM J, 47, 483 (1950); 3-CHLOROGLYCOLLANILIDE IN RABBIT: KIESE, M & LENK, W, BIOCHEM PHARMAC, 20, 379 (1971). /FROM TABLE/
• WHEN INCUBATED WITH RABBIT LIVER MICROSOMES, 3-CHLOROACETANILIDE WAS HYDROXYLATED IN THE 4-POSITION TO 3-CHLORO-4-HYDROXYACETANILIDE.

Synonyms

3'-Chloroacetanilide; 588-07-8; N-(3-Chlorophenyl)acetamide; 3-Chloroacetanilide; M-CHLOROACETANILIDE; Acetanilide, 3'-chloro-; meta-Chloroacetanilide; Acetic acid, amide, N(3-chlorophenyl)-; 74H09HU61J; NSC-6116; NSC-39967; DTXSID6060420; RefChem:154864; DTXCID8042474; 209-610-3; Acetamide, N-(3-chlorophenyl)-

Frequently Asked Questions

What are the CAS number and molecular formula of 3'-chloroacetanilide?

CAS 588-07-8; molecular formula C8H8ClNO; molecular weight — g/mol.

What other names is 3'-chloroacetanilide known by?

3'-Chloroacetanilide, 588-07-8, N-(3-Chlorophenyl)acetamide, 3-Chloroacetanilide, M-CHLOROACETANILIDE, Acetanilide, 3'-chloro-.

Is 3'-chloroacetanilide classified as hazardous?

Hazard statements reported: H315, H319, H335.

What are the key physical properties of 3'-chloroacetanilide?

Melting Point: 77-78 °C; Vapor Pressure: 0.0000963 [mmHg]; LogP: 2.02.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.