4-氨基-3,5,6-三氯吡啶甲酸

Description

4-amino-3,5,6-trichloropicolinic acid · CAS 1918-02-1 · C6H3Cl3N2O2. UNII O7437X49DW. Melting Point: 218.5 °C; Solubility: In water, 430 mg/L at 25 °C; Solubility: 0.04%.

Identification

CAS Registry Number	1918-02-1
PubChem CID	15965
Molecular formula	C6H3Cl3N2O2
IUPAC name	4-amino-3,5,6-trichloropyridine-2-carboxylic acid
UNII (FDA)	O7437X49DW

Computed Descriptors

Molecular Weight	241.5
XLogP3	2.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	1
Exact Mass	239.926010
Monoisotopic Mass	239.926010
Topological Polar Surface Area	76.2
Heavy Atom Count	13
Formal Charge	0

Physical & Chemical Properties

Melting Point	218.5 °C
Solubility	In water, 430 mg/L at 25 °C
Solubility	0.04%
Vapor Pressure	6.16e-07 mmHg at 95 °F (NTP, 1992)
Vapor Pressure	6.0X10-16 mm Hg at 25 °C
Vapor Pressure	0.0000006 mmHg at 95 °F
Vapor Pressure	(95 °F): 0.0000006 mmHg
LogP	log Kow = 0.30
LogP	1.9
LogP	1.0

Physical description & handling notes

• Picloram appears as fine beige crystals or white powder. Odor of chlorine. (NTP, 1992)
• Colorless to white crystals with a chlorine-like odor. [herbicide]; [NIOSH]
• COLOURLESS CRYSTALS OR WHITE POWDER WITH CHARACTERISTIC ODOUR.
• Fine beige crystals or white powder with a chlorine-like odor.
• Colorless to white crystals with a chlorine-like odor. [herbicide]
• White powder

Regulatory Status

GHS notification summary	2.3% (3 / 132)

GHS Hazard Classification

GHS notification summary	2.3% (3 / 132)
Reported hazard statements	H319 (31.8%), H400 (42.4%), H410 (44.7%), H412 (23.5%), H335, H373, H303, H316

Documented Uses

• Used to control woody plants and broad-leaved weeds in range management programs; [EXTOXNET]
• For deep-rooted broadleaf weeds and woody plants. Most grasses are resistant. Non-crop use in brush control along utility rights-of-way on forest sites, for weed and brush control in pastures and rangeland, and broadleaf weed control in small grains.
• An herbicide used as a defoliant in forest warfare.
• Produced by chlorination of 2-methylpyridine, hydrolysis and reaction with ammonia ...
• Picloram is produced from alpha-picoline by chlorination, followed by hydrolysis of the alpha-trichloropicoline derivative, and amidation.
• 2-Pyridinecarboxylic acid, 4-amino-3,5,6-trichloro- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and/or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B; 51FR21438).

Synonyms

PICLORAM; 1918-02-1; 4-Amino-3,5,6-trichloropyridine-2-carboxylic acid; 4-Amino-3,5,6-trichloropicolinic acid; Tordon; Borolin; Amdon; K-Pin; 2-Pyridinecarboxylic acid, 4-amino-3,5,6-trichloro-; Grazon; ATCP; Tordon 22K; Piclorame; Tordon 10K; Amdon grazon; 4-Aminotrichloropicolinic acid

Frequently Asked Questions

What are the CAS number and molecular formula of 4-amino-3,5,6-trichloropicolinic acid?

CAS 1918-02-1; molecular formula C6H3Cl3N2O2; molecular weight — g/mol.

What other names is 4-amino-3,5,6-trichloropicolinic acid known by?

PICLORAM, 1918-02-1, 4-Amino-3,5,6-trichloropyridine-2-carboxylic acid, 4-Amino-3,5,6-trichloropicolinic acid, Tordon, Borolin.

Is 4-amino-3,5,6-trichloropicolinic acid classified as hazardous?

2.3% of GHS notifications report no hazard classification (3 of 132).

What are the key physical properties of 4-amino-3,5,6-trichloropicolinic acid?

Melting Point: 218.5 °C; Solubility: In water, 430 mg/L at 25 °C; Solubility: 0.04%; Vapor Pressure: 6.16e-07 mmHg at 95 °F (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.