4-Aminoantipyrene

Description

4-Aminoantipyrene · CAS 83-07-8 · C11H13N3O. UNII 0M0B7474RA. Collision Cross Section: 156.8 Ų [M+Na]+; Collision Cross Section: 142.48 Ų [M+H]+.

Identification

CAS Registry Number	83-07-8
PubChem CID	2151
Molecular formula	C11H13N3O
IUPAC name	4-amino-1,5-dimethyl-2-phenylpyrazol-3-one
UNII (FDA)	0M0B7474RA

Computed Descriptors

Molecular Weight	203.24
XLogP3	0.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	203.105862047
Monoisotopic Mass	203.105862047
Topological Polar Surface Area	49.6
Heavy Atom Count	15
Formal Charge	0

Physical & Chemical Properties

Collision Cross Section	156.8 Ų [M+Na]+
Collision Cross Section	142.48 Ų [M+H]+

Physical description & handling notes

• 151.49 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 141.76 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 154.44 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 135.51 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 142.6 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

GHS notification summary	1% (1 / 105)

GHS Hazard Classification

GHS notification summary	1% (1 / 105)
Reported hazard statements	H302 (99%), H315 (90.5%), H319 (92.4%), H335 (88.6%)

Documented Uses

• Pharmaceuticals -> Animal Drugs -> Approved in Taiwan
• Pharmaceuticals -> Nervous System -> Analgesics -> Pyrazolones -> Transformation products
• 3H-Pyrazol-3-one, 4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-: ACTIVE
• 4-Aminoantipyrine is a known transformation product of 4-Formylaminoantipyrine, Aminopyrine, and 4-Acetamidoantipyrine.
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

Synonyms

4-Aminoantipyrine; AMPYRONE; 83-07-8; 4-Aminophenazone; Aminoantipyrine; Metapirazone; Aminoantipyrin; 4-Aminoantipyrene; Solvapyrin-A; Aminoazophene; Aminoazophenazone; Solnapyrin-A; 4-AAP; 4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one; 3H-Pyrazol-3-one, 4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-; 4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one

Frequently Asked Questions

What are the CAS number and molecular formula of 4-Aminoantipyrene?

CAS 83-07-8; molecular formula C11H13N3O; molecular weight — g/mol.

What other names is 4-Aminoantipyrene known by?

4-Aminoantipyrine, AMPYRONE, 83-07-8, 4-Aminophenazone, Aminoantipyrine, Metapirazone.

Is 4-Aminoantipyrene classified as hazardous?

1% of GHS notifications report no hazard classification (1 of 105).

What are the key physical properties of 4-Aminoantipyrene?

Collision Cross Section: 156.8 Ų [M+Na]+; Collision Cross Section: 142.48 Ų [M+H]+.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.