4'-氨基苯丙酮

Description

4'-aminopropiophenone · CAS 70-69-9 · C9H11NO. UNII 79GF917W6U. Boiling Point: 306.9 °C @760 [mm Hg]; Melting Point: 284 °F (EPA, 1998); Melting Point: 140 °C.

Identification

CAS Registry Number	70-69-9
PubChem CID	6270
Molecular formula	C9H11NO
IUPAC name	1-(4-aminophenyl)propan-1-one
UNII (FDA)	79GF917W6U

Computed Descriptors

Molecular Weight	149.19
XLogP3	1.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	2
Exact Mass	149.084063974
Monoisotopic Mass	149.084063974
Topological Polar Surface Area	43.1
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

Boiling Point	306.9 °C @760 [mm Hg]
Melting Point	284 °F (EPA, 1998)
Melting Point	140 °C
Melting Point	137 °C
Solubility	In water, 352 mg/L at 37 °C
Density	1.11 @25 °C
Vapor Pressure	0.0003 [mm Hg] @25 °C
LogP	1.65

Physical description & handling notes

• Propiophenone, 4'-amino- appears as yellow needles. (EPA, 1998)
• Platelets from alcohol, water; needles from water
• Yellow needles from water
• Soluble in DMSO
• Soluble in alcohol
• Needles, yellowish cast, mp 198-199 °C. Freely soluble in water /p-Aminopropiophenone hydrochloride/

Documented Uses

• /p-Aminopropiophenone is used as a/ more effective and specific control of target pests (stoats, ferrets and feral cats) which will assist in reversing the decline in indigenous biota (specifically, protected bird species such as the kiwi). ... PAPP Paste A, PAPP Paste B and PAPP Ready-to-use Bait are intended to be used as vertebrate toxic agents.
• Prepared by the action of propionyl chloride on aniline in carbon bisulfide in the presence of aluminum chloride.
• 1-Propanone, 1-(4-aminophenyl)-: ACTIVE
• /EXPERIMENTAL THERAPY:/ ... Of twelve compounds that had been found to exhibit high radioprotective activity by ip injection, only two p-aminopropiophenone and its ethylene ketal retain that high activity (92-95 % survivors) when administered orally...
• THERAPEUTIC CATEGORY: Antidote (cyanide)
• Drugs used to protect against ionizing radiation. They are usually of interest for use in radiation therapy but have been considered for other purposes, e.g. military.

Synonyms

4'-Aminopropiophenone; 70-69-9; 1-(4-aminophenyl)propan-1-one; p-Aminopropiophenone; 4-Aminopropiophenone; 1-(4-Aminophenyl)-1-propanone; 1-Propanone, 1-(4-aminophenyl)-; USAF uctl-1856; Ethyl p-aminophenyl ketone; Paraminopropiophenone; NSC-3187; 79GF917W6U; DTXSID7021738; RefChem:95920; DTXCID601738; 200-742-7

Frequently Asked Questions

What are the CAS number and molecular formula of 4'-aminopropiophenone?

CAS 70-69-9; molecular formula C9H11NO; molecular weight — g/mol.

What other names is 4'-aminopropiophenone known by?

4'-Aminopropiophenone, 70-69-9, 1-(4-aminophenyl)propan-1-one, p-Aminopropiophenone, 4-Aminopropiophenone, 1-(4-Aminophenyl)-1-propanone.

What are the key physical properties of 4'-aminopropiophenone?

Boiling Point: 306.9 °C @760 [mm Hg]; Melting Point: 284 °F (EPA, 1998); Melting Point: 140 °C; Melting Point: 137 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.