5,7-二碘-8-羟基喹啉

Description

5,7-diiodo-8-hydroxyquinoline · CAS 83-73-8 · C9H5I2NO. UNII 63W7IE88K8. LogP: 2.49.

Identification

CAS Registry Number	83-73-8
PubChem CID	3728
Molecular formula	C9H5I2NO
IUPAC name	5,7-diiodoquinolin-8-ol
UNII (FDA)	63W7IE88K8

Computed Descriptors

Molecular Weight	396.95
XLogP3	3.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	396.84606
Monoisotopic Mass	396.84606
Topological Polar Surface Area	33.1
Heavy Atom Count	13
Formal Charge	0

Physical & Chemical Properties

LogP	2.49

Physical description & handling notes

• CRYSTALS FROM XYLENE; MEDICINAL GRADE IS YELLOWISH-BROWN POWDER
• ABOVE 150 DEG, SUBLIMATES OF NEEDLES, PRISMS & RODS; ABOVE 200 DEG BROWN DROPS; MELT TURNS DARK-BROWN
• LIGHT YELLOWISH TO TAN, MICROCRYSTALLINE POWDER
• ODORLESS OR NEARLY SO
• MP 200-215 °C WITH EXTENSIVE DECOMP
• ALMOST INSOL IN WATER; SPARINGLY SOL IN ALCOHOL, ETHER, ACETONE; SOL IN HOT PYRIDINE & HOT DIOXANE

GHS Hazard Classification

Reported hazard statements	H302 (98.5%), H312 (37.3%), H315 (38.8%), H318 (59.7%), H319 (37.3%), H332 (37.3%), H335 (37.3%)

Documented Uses

• PREPD BY ACTION OF IODINE MONOCHLORIDE ON 8-HYDROXYQUINOLINE: PAPESCH, BURTNER, J AM CHEM SOC 58, 1314 (1936): BY ACTION OF KIO3 ON 8-HYDROXYQUINOLINE: ZIEFMAN, CA 34, 3745. ELECTROLYTIC PREPN: BROWN, BERKOWITZ, TRANS ELECTROCHEM SOC 75, 385 (1939) SEE ALSO CLAUS GER PAT 78,880; PASSEK, GER PAT 411,050...
• 8-Quinolinol, 5,7-diiodo-: ACTIVE
• Used in the treatment of amoebiasis.
• Diiodohydroxyquinoline (Class: Other Substances, Added Date: 12-1999)
• Amebicides; Anti-Infective Agents, Local
• ...MAY BE USED IN LOCAL & SYSTEMIC TREATMENT OF TRICHOMONAS VAGINALIS VAGINITIS & INFECTIONS CAUSED BY TRICHOMONAS HOMINIS (INTESTINALIS). IT IS USED IN TOPICAL TREATMENT OF CERTAIN FUNGAL CUTANEOUS INFECTIONS & IN ECZEMA IN WHICH FUNGAL INFECTION IS COMPLICATION.

Synonyms

iodoquinol; 83-73-8; Diiodohydroxyquinoline; 5,7-diiodoquinolin-8-ol; 5,7-Diiodo-8-hydroxyquinoline; Diodoquin; Searlequin; Zoaquin; Ioquin; Lanodoxin; Quinadome; Diodohydroxyquin; Dinoleine; Diodoxylin; Direxiode; Enterosept

Frequently Asked Questions

What are the CAS number and molecular formula of 5,7-diiodo-8-hydroxyquinoline?

CAS 83-73-8; molecular formula C9H5I2NO; molecular weight — g/mol.

What other names is 5,7-diiodo-8-hydroxyquinoline known by?

iodoquinol, 83-73-8, Diiodohydroxyquinoline, 5,7-diiodoquinolin-8-ol, 5,7-Diiodo-8-hydroxyquinoline, Diodoquin.

Is 5,7-diiodo-8-hydroxyquinoline classified as hazardous?

Hazard statements reported: H302, H312, H315, H318, H319.

What are the key physical properties of 5,7-diiodo-8-hydroxyquinoline?

LogP: 2.49.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.