Acetovanillone

Description

4-Hydroxy-3-methoxyacetophenone · CAS 498-02-2 · C9H10O3. UNII B6J7B9UDTR.

Identification

CAS Registry Number	498-02-2
PubChem CID	2214
Molecular formula	C9H10O3
IUPAC name	1-(4-hydroxy-3-methoxyphenyl)ethanone
UNII (FDA)	B6J7B9UDTR

Computed Descriptors

Molecular Weight	166.17
XLogP3	0.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	166.062994177
Monoisotopic Mass	166.062994177
Topological Polar Surface Area	46.5
Heavy Atom Count	12
Formal Charge	0

Regulatory Status

Regulatory & Food Contact	EU Flavoring substances Flavoring Agents
GHS notification summary	65.7% (94 / 143)

GHS Hazard Classification

GHS notification summary	65.7% (94 / 143)
Reported hazard statements	H315 (34.3%), H319 (34.3%), H335 (33.6%)

Documented Uses

• Ethanone, 1-(4-hydroxy-3-methoxyphenyl)-: ACTIVE
• Apocynin (Class: Other Substances, Added Date: 11-2014)
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues.
• Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

Synonyms

Acetovanillone; apocynin; 498-02-2; 4'-Hydroxy-3'-methoxyacetophenone; 1-(4-Hydroxy-3-methoxyphenyl)ethanone; Acetoguaiacone; 4-Acetyl-2-methoxyphenol; Apocynine; Acetoguaiacon; 1-(4-hydroxy-3-methoxyphenyl)ethan-1-one; Ethanone, 1-(4-hydroxy-3-methoxyphenyl)-; 4-Hydroxy-3-methoxyphenyl methyl ketone; B6J7B9UDTR; NSC-209524; DTXSID7060097; CHEBI:2781

Frequently Asked Questions

What are the CAS number and molecular formula of 4-Hydroxy-3-methoxyacetophenone?

CAS 498-02-2; molecular formula C9H10O3; molecular weight — g/mol.

What other names is 4-Hydroxy-3-methoxyacetophenone known by?

Acetovanillone, apocynin, 498-02-2, 4'-Hydroxy-3'-methoxyacetophenone, 1-(4-Hydroxy-3-methoxyphenyl)ethanone, Acetoguaiacone.

What is the regulatory status of 4-Hydroxy-3-methoxyacetophenone?

Documented regulatory listings: EU Flavoring substances; Flavoring Agents.

Is 4-Hydroxy-3-methoxyacetophenone classified as hazardous?

65.7% of GHS notifications report no hazard classification (94 of 143).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.