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Adriamycin

CAS 23214-92-8C27H29NO11MW 543.5

Adriamycin (CAS No. 23214-92-8) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number23214-92-8
Molecular FormulaC27H29NO11
Molecular Weight543.5
Melting Point229-231 °C
LogP1.27
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Adriamycin?

The CAS number of Adriamycin is 23214-92-8.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Adriamycin?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Adriamycin or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Adriamycin · CAS 23214-92-8 · C27H29NO11. UNII 80168379AG. Melting Point: 229-231 °C; Melting Point: 230 °C; Melting Point: 204 - 205 °C.

Identification

CAS Registry Number23214-92-8
PubChem CID31703
Molecular formulaC27H29NO11
IUPAC name(7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
UNII (FDA)80168379AG

Computed Descriptors

Molecular Weight543.5
XLogP31.3
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count12
Rotatable Bond Count5
Exact Mass543.17406074
Monoisotopic Mass543.17406074
Topological Polar Surface Area206
Heavy Atom Count39
Formal Charge0

Physical & Chemical Properties

Melting Point229-231 °C
Melting Point230 °C
Melting Point204 - 205 °C
Solubility~10 mg/ml
Solubility1.18e+00 g/L
LogP1.27
LogPlog Kow = 1.27
LogP-0.5
LogP0.6

Physical description & handling notes

  • Solid
  • Red, crystalline solid
  • MELTING POINT: 205 °C WITH DECOMP; PKA: 8.22; ALMOST ODORLESS; HYGROSCOPIC /HYDROCHLORIDE/
  • 2% sol in water; soluble in aqueous alcohols; moderately soluble in anhydrous methanol; insoluble in non-polar organic solvents
  • Neutral aq soln are stable at room temp
  • Specific optical rotation: +248 deg at 20 °C/D (0.1% in methanol)

GHS Hazard Classification

Reported hazard statementsH302 (100%), H350 (100%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H350 (100%): May cause cancer [Danger Carcinogenicity]

Documented Uses

  • Therapeutic Category: Antineoplastic
  • Consumption (g per capita) in the USA (2002): 4.29e-06
  • Adriamycin is a cytotoxic antibiotic isolated from cultures of Streptomyces peucetius var. caesius, a mutant obtained by treating Streptomyces peucetius with N-nitroso-N-methylurethane. /Doxorubicin hydrochloride/
  • (8S,10S)-10[(3-amino-2,3,6-trideoxy-alpha-levo-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
  • Doxorubicin is an antibiotic derived from the Streptomyces peucetius bacterium. Since the 1960s, doxorubicin has been widely used as a chemotherapeutic agent. Doxorubicin belongs to the anthracycline class of chemotherapeutic agents; other anthracyclines include daunorubicin, idarubicin, and epirubicin. Doxorubicin is commonly used to treat solid tumors in both adult and pediatric patients.
  • Breast Feeding; Lactation; Milk, Human; Antineoplastic Agents; Anthracyclines; Antibiotics, Antineoplastic; Topoisomerase II Inhibitors

Synonyms

doxorubicin; Adriamycin; 23214-92-8; Adriablastin; Doxorubicine; 14-Hydroxydaunomycin; Doxorubicinum; Doxorubicina; 14-Hydroxydaunorubicine; NDC 38242-874; NSC 123127; NSC-123127; NSC-759155; 80168379AG; DTXSID8021480; CHEBI:28748

Frequently Asked Questions

What are the CAS number and molecular formula of Adriamycin?

CAS 23214-92-8; molecular formula C27H29NO11; molecular weight — g/mol.

What other names is Adriamycin known by?

doxorubicin, Adriamycin, 23214-92-8, Adriablastin, Doxorubicine, 14-Hydroxydaunomycin.

Is Adriamycin classified as hazardous?

Hazard statements reported: H302, H350.

What are the key physical properties of Adriamycin?

Melting Point: 229-231 °C; Melting Point: 230 °C; Melting Point: 204 - 205 °C; Solubility: ~10 mg/ml.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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