Alprostadil

Name: Alprostadil
Brand: Jinan Shenghe Chemical Co., Ltd.

CAS 745-65-3C20H34O5MW 354.5

Alprostadil (CAS No. 745-65-3) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number745-65-3

Molecular FormulaC20H34O5

Molecular Weight354.5

Melting Point115-116 °C

LogP3.2

Purity按批次COA提供(不公开发布)

Packaging按订单/批次确认(不公开发布)

ApplicationsPharmaceutical Intermediates & APIs

CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)

Purity按批次COA提供(不公开发布)

StorageSealed, cool and dry place

Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Alprostadil?

The CAS number of Alprostadil is 745-65-3.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Alprostadil?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Alprostadil or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Alprostadil · CAS 745-65-3 · C20H34O5. UNII F5TD010360. Melting Point: 115-116 °C; Melting Point: 115 - 116 °C; Solubility: 26.7.

Identification

CAS Registry Number	745-65-3
PubChem CID	5280723
Molecular formula	C20H34O5
IUPAC name	7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
UNII (FDA)	F5TD010360

Computed Descriptors

Molecular Weight	354.5
XLogP3	3.2
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	13
Exact Mass	354.24062418
Monoisotopic Mass	354.24062418
Topological Polar Surface Area	94.8
Heavy Atom Count	25
Formal Charge	0

Physical & Chemical Properties

Melting Point	115-116 °C
Melting Point	115 - 116 °C
Solubility	26.7
LogP	3.2
LogP	3.20
Dissociation Constants	4.87
Dissociation Constants	4.85 (at 25 °C)

Physical description & handling notes

Solid
190.6 Å² [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Calculation: Single Field; Dataset: Oxylipins]
198.3 Å² [M+Na]+ [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
181.94 Å² [M-H2O-H]- [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]

GHS Hazard Classification

Reported hazard statements	H301 (100%), H361 (56.8%)

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

H361 (56.8%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

Alprostadil is indicated for palliative, not definitive, therapy to temporarily maintain the patency of the ductus arteriosus until corrective or palliative surgery can be performed in neonates who have congenital heart defects and who depend upon the patent ductus for survival. It is also indicated for the treatment of erectile dysfunction due to neurogenic, vasculogenic, psychogenic, or mixed etiology, and as an adjunct to other diagnostic tests in the diagnosis of erectile dysfunction.
Medicines administered to the neonate [c]
Parenteral - General injections - IV: 0.5 mg per mL in alcohol
Other specified congenital anomaly of great arteries including arterial duct
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
Drugs used to cause dilation of the blood vessels.

Synonyms

alprostadil; Prostaglandin E1; 745-65-3; PGE1; Caverject; Edex; Muse; Alprostadilum; Befar; Prostin VR Pediatric; Vitaros; Prink; PGE-1; Prostavasin; (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid; Caverject Impulse

Frequently Asked Questions

What are the CAS number and molecular formula of Alprostadil?

CAS 745-65-3; molecular formula C20H34O5; molecular weight — g/mol.

What other names is Alprostadil known by?

alprostadil, Prostaglandin E1, 745-65-3, PGE1, Caverject, Edex.

Is Alprostadil classified as hazardous?

Hazard statements reported: H301, H361.

What are the key physical properties of Alprostadil?

Melting Point: 115-116 °C; Melting Point: 115 - 116 °C; Solubility: 26.7; LogP: 3.2.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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