Ammonium Sulfobituminate

Description

Ichthammol · CAS 8029-68-3 · CH4N2O2. UNII X6Q56QN5QC. Melting Point: 133-136; Melting Point: 141 °C; Melting Point: 142 - 146 °C.

Identification

CAS Registry Number	8029-68-3
PubChem CID	3657
Molecular formula	CH4N2O2
IUPAC name	hydroxyurea
UNII (FDA)	X6Q56QN5QC

Computed Descriptors

Molecular Weight	76.055
XLogP3	-1.8
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	76.027277375
Monoisotopic Mass	76.027277375
Topological Polar Surface Area	75.4
Heavy Atom Count	5
Formal Charge	0

Physical & Chemical Properties

Melting Point	133-136
Melting Point	141 °C
Melting Point	142 - 146 °C
Solubility	1000000
Solubility	2.69e+02 g/L
LogP	-1.8
LogP	log Kow = -1.80
LogP	-1.6
LogP	-1.27

Physical description & handling notes

• Hydroxyurea appears as odorless or almost odorless white to off-white crystalline solid. Tasteless. (NTP, 1992)
• Solid
• Needles from alcohol
• White, crystalline powder
• Needles from ethanol, crystals in 2 forms
• Decomposes (NTP, 1992)

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Antimicrobial

GHS Hazard Classification

Reported hazard statements	H340 (86.2%), H360 (13.8%), H361 (82.8%)

Documented Uses

• Antineoplastic Agents; Antisickling Agents; Enzyme Inhibitors; Nucleic Acid Synthesis Inhibitors
• Use (kg; approx.) in Germany (2009): >5000
• Use (kg; exact) in Germany (2009): 5996
• Consumption (g per capita; approx.) in Germany (2009): 0.0611
• Consumption (g per capita; exact) in Germany (2009): 0.0732
• For management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia.

Synonyms

hydroxyurea; 127-07-1; Hydroxycarbamide; N-Hydroxyurea; Hydrea; Oxyurea; Carbamoyl oxime; Carbamohydroxamic acid; Carbamohydroximic acid; Litalir; Hydroxycarbamine; Urea, hydroxy-; Onco-carbide; Biosupressin; Droxia; Hidrix

Frequently Asked Questions

What are the CAS number and molecular formula of Ichthammol?

CAS 8029-68-3; molecular formula CH4N2O2; molecular weight — g/mol.

What other names is Ichthammol known by?

hydroxyurea, 127-07-1, Hydroxycarbamide, N-Hydroxyurea, Hydrea, Oxyurea.

What is the regulatory status of Ichthammol?

Documented regulatory listings: CIR / INCI: Antimicrobial.

Is Ichthammol classified as hazardous?

Hazard statements reported: H340, H360, H361.

What are the key physical properties of Ichthammol?

Melting Point: 133-136; Melting Point: 141 °C; Melting Point: 142 - 146 °C; Solubility: 1000000.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.