Amrinone

Description

Amrinone · CAS 60719-84-8 · C10H9N3O. UNII JUT23379TN. Melting Point: 294-297; Melting Point: 295 °C; Solubility: 5.60e+00 g/L.

Identification

CAS Registry Number	60719-84-8
PubChem CID	3698
Molecular formula	C10H9N3O
IUPAC name	3-amino-5-pyridin-4-yl-1H-pyridin-2-one
UNII (FDA)	JUT23379TN

Computed Descriptors

Molecular Weight	187.20
XLogP3	-0.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	187.074561919
Monoisotopic Mass	187.074561919
Topological Polar Surface Area	68
Heavy Atom Count	14
Formal Charge	0

Physical & Chemical Properties

Melting Point	294-297
Melting Point	295 °C
Solubility	5.60e+00 g/L
LogP	0.54

Physical description & handling notes

• Solid
• >28.1 [ug/mL] (The mean of the results at pH 7.4)
• 142.7 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID9022603]
• 140.7 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID9022603]
• 143.3 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID9022603]
• 139 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H301 (100%)

Documented Uses

• Used in the treatment of congestive heart failure.
• A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
• Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
• Drugs used to cause dilation of the blood vessels.
• Compounds that specifically inhibit PHOSPHODIESTERASE 3.
• C01C - Cardiac stimulants excl. cardiac glycosides

Synonyms

Amrinone; 60719-84-8; inamrinone; Cartonic; Amcoral; Vesistol; Amrinona; Amrinonum; WIN 40680; DTXSID9022603; [3,4'-Bipyridin]-6(1H)-one, 5-amino-; 5-Amino(3,4'-bipyridin)-6(1H)-one; NSC-759805; CHEBI:2686; JUT23379TN; (3,4'-BIPYRIDIN)-6(1H)-ONE, 5-AMINO-

Frequently Asked Questions

What are the CAS number and molecular formula of Amrinone?

CAS 60719-84-8; molecular formula C10H9N3O; molecular weight — g/mol.

What other names is Amrinone known by?

Amrinone, 60719-84-8, inamrinone, Cartonic, Amcoral, Vesistol.

Is Amrinone classified as hazardous?

Hazard statements reported: H301.

What are the key physical properties of Amrinone?

Melting Point: 294-297; Melting Point: 295 °C; Solubility: 5.60e+00 g/L; LogP: 0.54.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.