子囊霉素

Description

Ascomycin · CAS 104987-12-4 · C43H69NO12. UNII AUF4U5NSJK.

Identification

CAS Registry Number	104987-12-4
PubChem CID	5282071
Molecular formula	C43H69NO12
IUPAC name	(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-17-ethyl-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
UNII (FDA)	AUF4U5NSJK

Computed Descriptors

Molecular Weight	792.0
XLogP3	2.5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	6
Exact Mass	791.48197664
Monoisotopic Mass	791.48197664
Topological Polar Surface Area	178
Heavy Atom Count	56
Formal Charge	0

GHS Hazard Classification

Reported hazard statements	H302 (100%), H312 (100%), H332 (100%), H351 (100%), H361 (100%), H413 (100%), H373 (100%)

Documented Uses

• Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
• Substances that inhibit the growth or reproduction of BACTERIA.

Synonyms

ascomycin; Immunomycin; 104987-12-4; FK520; Changchuanmycin; AUF4U5NSJK; L-683590; FK-520; NSC-106410; CHEBI:29582; DTXSID80894126; FR-520; RefChem:916297; DTXCID201324166; 435-850-5; FK 520

Frequently Asked Questions

What are the CAS number and molecular formula of Ascomycin?

CAS 104987-12-4; molecular formula C43H69NO12; molecular weight — g/mol.

What other names is Ascomycin known by?

ascomycin, Immunomycin, 104987-12-4, FK520, Changchuanmycin, AUF4U5NSJK.

Is Ascomycin classified as hazardous?

Hazard statements reported: H302, H312, H332, H351, H361.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.