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Azathioprine

CAS 446-86-6C9H7N7O2SMW 277.27

Azathioprine (CAS No. 446-86-6) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number446-86-6
Molecular FormulaC9H7N7O2S
Molecular Weight277.27
Melting Point243.5
LogP0.1
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Azathioprine?

The CAS number of Azathioprine is 446-86-6.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Azathioprine?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Azathioprine or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Azathioprine · CAS 446-86-6 · C9H7N7O2S. UNII MRK240IY2L. Melting Point: 243.5; Melting Point: dec 243-244 °C; Melting Point: 243.5 °C.

Identification

CAS Registry Number446-86-6
PubChem CID2265
Molecular formulaC9H7N7O2S
IUPAC name6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
UNII (FDA)MRK240IY2L

Computed Descriptors

Molecular Weight277.27
XLogP30.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Exact Mass277.03819367
Monoisotopic Mass277.03819367
Topological Polar Surface Area143
Heavy Atom Count19
Formal Charge0

Physical & Chemical Properties

Melting Point243.5
Melting Pointdec 243-244 °C
Melting Point243.5 °C
Solubility1.07e+00 g/L
LogP0.1
LogPlog Kow = 0.10
LogP0.7
LogP0.89
Dissociation Constants7.87 (at 25 °C)
Dissociation ConstantspKa = 8.2

Physical description & handling notes

  • Azathioprine appears as pale yellow crystals or yellowish powder. Decomposes at 243-244 °C. Used for the treatment of rheumatoid arthritis. A known carcinogen.
  • Solid
  • Pale yellow crystals from 50% aq acetone
  • 469 to 471 °F (decomposes) (NTP, 1992)
  • less than 1 mg/mL at 73 °F (NTP, 1992)
  • Insoluble

GHS Hazard Classification

Reported hazard statementsH302 (100%), H315 (88.8%), H319 (88.8%), H335 (87.9%), H340 (62.6%), H350 (100%), H360 (58.9%), H317

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (88.8%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

  • Used as an immunosuppressant and anticancer drug; [Kanerva, p. 1753]
  • Use (kg; approx.) in Germany (2009): >2500
  • Use (kg; exact) in Germany (2009): 3323
  • Consumption (g per capita; approx.) in Germany (2009): 0.0305
  • Consumption (g per capita; exact) in Germany (2009): 0.0406
  • Consumption (g per capita) in the USA (2002): 0.00253

Synonyms

azathioprine; 446-86-6; Azothioprine; Azanin; Azathioprin; Azatioprin; Azamun; Azasan; Ccucol; Imurek; Muran; NSC-39084; Azathioprinum; Azatioprina; BW 57-322; BW-57-322

Frequently Asked Questions

What are the CAS number and molecular formula of Azathioprine?

CAS 446-86-6; molecular formula C9H7N7O2S; molecular weight — g/mol.

What other names is Azathioprine known by?

azathioprine, 446-86-6, Azothioprine, Azanin, Azathioprin, Azatioprin.

Is Azathioprine classified as hazardous?

Hazard statements reported: H302, H315, H319, H335, H340.

What are the key physical properties of Azathioprine?

Melting Point: 243.5; Melting Point: dec 243-244 °C; Melting Point: 243.5 °C; Solubility: 1.07e+00 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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