硫唑嘌呤钠

Description

Azathioprine Sodium · CAS 55774-33-9 · C9H6N7NaO2S. UNII AM94R510MS.

Identification

CAS Registry Number	55774-33-9
PubChem CID	11529527
Molecular formula	C9H6N7NaO2S
IUPAC name	sodium 6-(3-methyl-5-nitroimidazol-4-yl)sulfanylpurin-9-ide
UNII (FDA)	AM94R510MS

Computed Descriptors

Molecular Weight	299.25
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	2
Exact Mass	299.02013792
Monoisotopic Mass	299.02013792
Topological Polar Surface Area	129
Heavy Atom Count	20
Formal Charge	0
Complexity	354

Documented Uses

• Drugs that are chemically similar to naturally occurring metabolites, but differ enough to interfere with normal metabolic pathways. (From AMA Drug Evaluations Annual, 1994, p2033)
• Antimetabolites that are useful in cancer chemotherapy.
• Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
• Drugs that are used to treat RHEUMATOID ARTHRITIS.
• Purine Antimetabolite [EPC]; Purines [CS]; Nucleosides [CS]; Nucleic Acid Synthesis Inhibitors [MoA]

Synonyms

Azathioprine sodium; 55774-33-9; Imuran injection; Azathioprine sodium salt; AM94R510MS; 1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-, sodium salt; RefChem:58528; Azathioprine Sodium [USP]; sodium;6-(3-methyl-5-nitroimidazol-4-yl)sulfanylpurin-9-ide; Sodium 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)purin-9-ide; UNII-AM94R510MS; starbld0014273; orb1740381; CHEMBL1200400; SCHEMBL30647265; WISNYKIQFMKSDQ-UHFFFAOYSA-N

Frequently Asked Questions

What are the CAS number and molecular formula of Azathioprine Sodium?

CAS 55774-33-9; molecular formula C9H6N7NaO2S; molecular weight — g/mol.

What other names is Azathioprine Sodium known by?

Azathioprine sodium, 55774-33-9, Imuran injection, Azathioprine sodium salt, AM94R510MS, 1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-, sodium salt.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.