阿洛西林

Description

Azlocillin · CAS 37091-66-0 · C20H23N5O6S. UNII HUM6H389W0. Solubility: 2.33e-01 g/L; LogP: 0.2.

Identification

CAS Registry Number	37091-66-0
PubChem CID	6479523
Molecular formula	C20H23N5O6S
IUPAC name	(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
UNII (FDA)	HUM6H389W0

Computed Descriptors

Molecular Weight	461.5
XLogP3	0.1
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	5
Exact Mass	461.13690464
Monoisotopic Mass	461.13690464
Topological Polar Surface Area	173
Heavy Atom Count	32
Formal Charge	0

Physical & Chemical Properties

Solubility	2.33e-01 g/L
LogP	0.2

Physical description & handling notes

• Solid
• Sodium salt is soluble in water (50 mg/ml)
• 210.14 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 204.77 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 211.84 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• Similar to [mezlocillin] and [piperacillin], azlocillin is an acylampicillin that exhibits an extended-spectrum of activity and _in vitro_ potency that is greater than that of the carboxy penicillins. Azlocillin is shown to be effective against a broad spectrum of bacteria, including <i>Pseudomonas aeruginosa</i> and enterococci.

Documented Uses

• For the treatment of infections caused by Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae.
• Substances that inhibit the growth or reproduction of BACTERIA.
• J - Antiinfectives for systemic use
• J01 - Antibacterials for systemic use
• J01C - Beta-lactam antibacterials, penicillins
• J01CA - Penicillins with extended spectrum

Synonyms

azlocillin; 37091-66-0; Azlocilina; Azlocilline; Azlocillinum; CHEBI:2956; HUM6H389W0; J01CA09; NSC-758227; DTXSID1022639; azlocillina; Azlocillin, Sodium; Sodium, Azlocillin; RefChem:560588; Baye 6905; Bay e 6905

Frequently Asked Questions

What are the CAS number and molecular formula of Azlocillin?

CAS 37091-66-0; molecular formula C20H23N5O6S; molecular weight — g/mol.

What other names is Azlocillin known by?

azlocillin, 37091-66-0, Azlocilina, Azlocilline, Azlocillinum, CHEBI:2956.

What are the key physical properties of Azlocillin?

Solubility: 2.33e-01 g/L; LogP: 0.2.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.