甘菊环

Description

Azulene · CAS 275-51-4 · C10H8. UNII 82R6M9MGLP. LogP: 3.22.

Identification

CAS Registry Number	275-51-4
PubChem CID	9231
Molecular formula	C10H8
IUPAC name	azulene
UNII (FDA)	82R6M9MGLP

Computed Descriptors

Molecular Weight	128.17
XLogP3	3.2
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	0
Rotatable Bond Count	0
Exact Mass	128.062600255
Monoisotopic Mass	128.062600255
Topological Polar Surface Area	0
Heavy Atom Count	10
Formal Charge	0

Physical & Chemical Properties

LogP	3.22

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Cosmetic ingredients (Azulene) -> CIR (Cosmetic Ingredient Review)
GHS notification summary	9.1% (4 / 44)

GHS Hazard Classification

GHS notification summary	9.1% (4 / 44)
Reported hazard statements	H411 (90.9%)

Documented Uses

• PAHs are released into the environment via the combustion of fossil fuels, coke oven emissions and vehicle exhausts, as well as naturally from forest fires and vocanic eruptions. PAHs from these sources may contaminate nearly water systems. They are also found in coal tar and charbroiled food. (L10)
• Azulene (Class: Other Substances, Added Date: 05-2017)
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• PAH metabolism occurs in all tissues, usually by cytochrome P-450 and its associated enzymes. PAHs are metabolized into reactive intermediates, which include epoxide intermediates, dihydrodiols, phenols, quinones, and their various combinations. The phenols, quinones, and dihydrodiols can all be conjugated to glucuronides and sulfate esters; the quinones also form glutathione conjugates. (L10)

Synonyms

azulene; 275-51-4; Cyclopentacycloheptene; Azunamic; Bicyclo[5.3.0]decapentaene; azulen; Bicyclo(5.3.0)decapentaene; Bicyclo(5.3.0)-deca-2,4,6,8,10-pentaene; 82R6M9MGLP; Bicyclo(5.3.0)-1,3,5,7,9-decapentaene; DTXSID2059770; NSC-89248; CHEBI:31249; RefChem:116159; DTXCID7037686; 205-993-6

Frequently Asked Questions

What are the CAS number and molecular formula of Azulene?

CAS 275-51-4; molecular formula C10H8; molecular weight — g/mol.

What other names is Azulene known by?

azulene, 275-51-4, Cyclopentacycloheptene, Azunamic, Bicyclo[5.3.0]decapentaene, azulen.

What is the regulatory status of Azulene?

Documented regulatory listings: CIR / INCI: Cosmetic ingredients (Azulene) -> CIR (Cosmetic Ingredient Review).

Is Azulene classified as hazardous?

9.1% of GHS notifications report no hazard classification (4 of 44).

What are the key physical properties of Azulene?

LogP: 3.22.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.