巴洛沙韦酯

Description

Baloxavir marboxil · CAS 1985606-14-1 · C27H23F2N3O7S. UNII 505CXM6OHG. Solubility: 0.015; LogP: 2.26.

Identification

CAS Registry Number	1985606-14-1
PubChem CID	124081896
Molecular formula	C27H23F2N3O7S
IUPAC name	[(3R)-2-[(11S)-7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl]-9,12-dioxo-5-oxa-1,2,8-triazatricyclo[8.4.0.03,8]tetradeca-10,13-dien-11-yl]oxymethyl methyl carbonate
UNII (FDA)	505CXM6OHG

Computed Descriptors

Molecular Weight	571.6
XLogP3	3.8
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	6
Exact Mass	571.12247758
Monoisotopic Mass	571.12247758
Topological Polar Surface Area	123
Heavy Atom Count	40
Formal Charge	0

Physical & Chemical Properties

Solubility	0.015
LogP	2.26

GHS Hazard Classification

Reported hazard statements	H411 (100%)

Documented Uses

• Avoid antacids. Baloxavir may form a chelate with polyvalent cations in antacids, which may decrease plasma concentrations of baloxavir.
• Avoid milk and dairy products. Baloxavir may form a chelate with polyvalent cations such as calcium in dairy products, which may decrease plasma concentrations of baloxavir.
• Avoid multivalent ions. Multivalent ions such as magnesium, calcium, and aluminum can form a chelate with baloxavir, which can reduce the absorption of baloxavir.
• Take with or without food. Food reduces drug absorption, but not to a clinically significant extent.
• Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
• Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

Synonyms

Baloxavir marboxil; 1985606-14-1; Xofluza; S-033188; 505CXM6OHG; DTXSID601027758; baloxavirum marboxilum; RefChem:56255; J05AX25; DTXCID301513437; 862-996-0; baloxavir-marboxil; MFCD31619272; Baloxavir marboxil [INN]; S033188; 1830312-72-5

Frequently Asked Questions

What are the CAS number and molecular formula of Baloxavir marboxil?

CAS 1985606-14-1; molecular formula C27H23F2N3O7S; molecular weight — g/mol.

What other names is Baloxavir marboxil known by?

Baloxavir marboxil, 1985606-14-1, Xofluza, S-033188, 505CXM6OHG, DTXSID601027758.

Is Baloxavir marboxil classified as hazardous?

Hazard statements reported: H411.

What are the key physical properties of Baloxavir marboxil?

Solubility: 0.015; LogP: 2.26.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.