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Baricitinib

CAS 1187594-09-7C16H17N7O2SMW 371.4

Baricitinib (CAS No. 1187594-09-7) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number1187594-09-7
Molecular FormulaC16H17N7O2S
Molecular Weight371.4
Boiling Point707.2
LogP-0.5
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Baricitinib?

The CAS number of Baricitinib is 1187594-09-7.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Baricitinib?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Baricitinib or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Baricitinib · CAS 1187594-09-7 · C16H17N7O2S. UNII ISP4442I3Y. Boiling Point: 707.2.

Identification

CAS Registry Number1187594-09-7
PubChem CID44205240
Molecular formulaC16H17N7O2S
IUPAC name2-[1-ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile
UNII (FDA)ISP4442I3Y

Computed Descriptors

Molecular Weight371.4
XLogP3-0.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass371.11644398
Monoisotopic Mass371.11644398
Topological Polar Surface Area129
Heavy Atom Count26
Formal Charge0

Physical & Chemical Properties

Boiling Point707.2

GHS Hazard Classification

Reported hazard statementsH302 (50%), H335 (16.7%), H360 (66.7%), H372 (16.7%), H373 (66.7%), H411 (66.7%)

H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]

H335 (16.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Documented Uses

  • Baricitinib is a disease-modifying antirheumatic drug (DMARD) indicated for rheumatoid arthritis when conventional DMARDs prove inadequate.
  • Baricitinib is an orally available small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, severe alopecia areata, and, in combination with remdesivir, severe COVID-19 in hospitalized patients requiring supplementary oxygen. Baricitinib is associated with transient and usually mild elevations in serum aminotransferase levels during therapy but has yet to be linked to cases of clinically apparent acute liver injury.
  • Breast Feeding; Lactation; Milk, Human; Antirheumatic Agents; Enzyme Inhibitors; Janus Kinase Inhibitors; JAK Inhibitors; Signal Transduction Inhibitors; Protein Kinase Inhibitors
  • Baricitinib (Class: Other Substances, Added Date: 03-2022)
  • Take with or without food. A high-fat meal can decrease the mean AUC and Cmax of baricitinib and delay Tmax, but not to a clinically singificant extent.
  • Established Pharmacologic Class [EPC] - Janus Kinase Inhibitor

Synonyms

Baricitinib; 1187594-09-7; olumiant; LY3009104; INCB028050; INCB 028050; INCB-028050; 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile; LY-3009104; LY 3009104; ISP4442I3Y; DTXCID5074719; CHEBI:95341; DTXSID30152228; L04AA37; 3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-(4-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)-1H-pyrazol-1-yl)-

Frequently Asked Questions

What are the CAS number and molecular formula of Baricitinib?

CAS 1187594-09-7; molecular formula C16H17N7O2S; molecular weight — g/mol.

What other names is Baricitinib known by?

Baricitinib, 1187594-09-7, olumiant, LY3009104, INCB028050, INCB 028050.

Is Baricitinib classified as hazardous?

Hazard statements reported: H302, H335, H360, H372, H373.

What are the key physical properties of Baricitinib?

Boiling Point: 707.2.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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