Bempedoic acid

Description

Bempedoic acid · CAS 738606-46-7 · C19H36O5. UNII 1EJ6Z6Q368. Melting Point: 87-92.

Identification

CAS Registry Number	738606-46-7
PubChem CID	10472693
Molecular formula	C19H36O5
IUPAC name	8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid
UNII (FDA)	1EJ6Z6Q368

Computed Descriptors

Molecular Weight	344.5
XLogP3	4.8
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	14
Exact Mass	344.25627424
Monoisotopic Mass	344.25627424
Topological Polar Surface Area	94.8
Heavy Atom Count	24
Formal Charge	0

Physical & Chemical Properties

Melting Point	87-92

GHS Hazard Classification

Reported hazard statements	H302 (33.3%), H319 (33.3%), H372 (33.3%), H373 (33.3%)

Documented Uses

• Bempedoic acid is a prescription-only, once-daily oral tablet administered to reduce low-density lipoprotein cholesterol (LDL-C) levels. The drug works by inhibiting cholesterol synthesis in the same pathway as statins and has shown promising results in reducing the risks of cardiovascular diseases. Bempedoic acid is specifically effective for patients who require additional LDL-C reduction despite maximally tolerated statin therapy. In addition, bempedoic acid therapy provides a beneficial option for patients who
• Breast Feeding; Lactation; Milk, Human; Anticholesteremic Agents; Hypolipidemic Agents; Enzyme Inhibitors
• Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.
• Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
• Substances which lower blood glucose levels.
• Established Pharmacologic Class [EPC] - Adenosine Triphosphate-Citrate Lyase Inhibitor

Synonyms

bempedoic acid; 738606-46-7; ETC-1002; 8-Hydroxy-2,2,14,14-tetramethylpentadecanedioic acid; Nexletol; ESP-55016; acido bempedoico; ETC1002; acide bempedoique; acidum bempedoicum; ETC 1002; ESP 55016; 1EJ6Z6Q368; Pentadecanedioic acid, 8-hydroxy-2,2,14,14-tetramethyl-; CHEBI:149601; DTXSID401027952

Frequently Asked Questions

What are the CAS number and molecular formula of Bempedoic acid?

CAS 738606-46-7; molecular formula C19H36O5; molecular weight — g/mol.

What other names is Bempedoic acid known by?

bempedoic acid, 738606-46-7, ETC-1002, 8-Hydroxy-2,2,14,14-tetramethylpentadecanedioic acid, Nexletol, ESP-55016.

Is Bempedoic acid classified as hazardous?

Hazard statements reported: H302, H319, H372, H373.

What are the key physical properties of Bempedoic acid?

Melting Point: 87-92.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.