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cabozantinib (S)-malate

CAS 1140909-48-3C32H30FN3O10MW 635.6

cabozantinib (S)-malate (CAS No. 1140909-48-3) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number1140909-48-3
Molecular FormulaC32H30FN3O10
Molecular Weight635.6
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of cabozantinib (S)-malate?

The CAS number of cabozantinib (S)-malate is 1140909-48-3.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of cabozantinib (S)-malate?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy cabozantinib (S)-malate or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

cabozantinib (S)-malate · CAS 1140909-48-3 · C32H30FN3O10. UNII DR7ST46X58.

Identification

CAS Registry Number1140909-48-3
PubChem CID25102846
Molecular formulaC32H30FN3O10
IUPAC name1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2S)-2-hydroxybutanedioic acid
UNII (FDA)DR7ST46X58

Computed Descriptors

Molecular Weight635.6
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count12
Rotatable Bond Count11
Exact Mass635.19152232
Monoisotopic Mass635.19152232
Topological Polar Surface Area194
Heavy Atom Count46
Formal Charge0
Complexity924

GHS Hazard Classification

Reported hazard statementsH302 (98.1%), H315 (94.2%), H319 (92.3%), H335 (92.3%), H360 (96.2%), H373 (98.1%)

H302 (98.1%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (94.2%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

  • Cabometyx (Cabozantinib-S-Malate)
  • Cabozantinib-s-malate is approved to treat:
  • • Differentiated thyroid cancer that has spread. It is used in adults and children aged 12 years and older who cannot receive radioactive iodine and whose cancer got worse after VEGFreceptor-targeted therapy. This use is approved for the Cabometyx brand of cabozantinib-s-malate.
  • • Hepatocellular carcinoma (a type of liver cancer). It is used in patients who have already been treated with sorafenib. This use is approved for the Cabometyx brand of cabozantinib-s-malate.
  • • Medullary thyroid cancer that has gotten worse and has spread to other parts of the body. This use is approved for the Cometriq brand of cabozantinib-s-malate.
  • • Neuroendocrine tumor of the pancreas or another organ that is well-differentiated, has spread, and cannot be removed by surgery. It is used in adults and children aged 12 years and older whose cancer has been treated. This use is approved for the Cabometyx brand of cabozantinib-s-malate.

Synonyms

Cabozantinib S-malate; 1140909-48-3; Cabozantinib malate; cabozantinib (S)-malate; Cabometyx; XL184; DR7ST46X58; CHEBI:72319; DTXSID60915949; RefChem:1080604; DTXCID501510465; Cabozantinib malate (XL184); Cabozantinib (S-malate); Cabozantinib L-Malate Salt; MFCD20923480; Cabozantinib s-malate [USAN]

Frequently Asked Questions

What are the CAS number and molecular formula of cabozantinib (S)-malate?

CAS 1140909-48-3; molecular formula C32H30FN3O10; molecular weight — g/mol.

What other names is cabozantinib (S)-malate known by?

Cabozantinib S-malate, 1140909-48-3, Cabozantinib malate, cabozantinib (S)-malate, Cabometyx, XL184.

Is cabozantinib (S)-malate classified as hazardous?

Hazard statements reported: H302, H315, H319, H335, H360.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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