Camptothecin

Name: Camptothecin
Brand: Jinan Shenghe Chemical Co., Ltd.

CAS 7689-03-4C20H16N2O4MW 348.4

Camptothecin (CAS No. 7689-03-4) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number7689-03-4

Molecular FormulaC20H16N2O4

Molecular Weight348.4

Melting Point275-277 °C

LogP1.74

Purity按批次COA提供(不公开发布)

Packaging按订单/批次确认(不公开发布)

ApplicationsPharmaceutical Intermediates & APIs

CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)

Purity按批次COA提供(不公开发布)

StorageSealed, cool and dry place

Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Camptothecin?

The CAS number of Camptothecin is 7689-03-4.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Camptothecin?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Camptothecin or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Camptothecin · CAS 7689-03-4 · C20H16N2O4. UNII XT3Z54Z28A. Melting Point: 275-277 °C; LogP: 1.74.

Identification

CAS Registry Number	7689-03-4
PubChem CID	24360
Molecular formula	C20H16N2O4
IUPAC name	(19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
UNII (FDA)	XT3Z54Z28A

Computed Descriptors

Molecular Weight	348.4
XLogP3	1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	1
Exact Mass	348.11100700
Monoisotopic Mass	348.11100700
Topological Polar Surface Area	79.7
Heavy Atom Count	26
Formal Charge	0

Physical & Chemical Properties

Melting Point	275-277 °C
LogP	1.74

Physical description & handling notes

178.35 Å² [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
178.86 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
163.42 Å² [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
181.9 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
Camptothecin demonstrated strong anticancer activity in preliminary clinical trials but also low solubility and adverse drug reaction. Camptothecin is believed to be a potent topoisomerase inhibitor that interferes with the essential function of topoisomerase in DNA replication.

GHS Hazard Classification

Reported hazard statements	H301 (98%), H340 (20%)

H301 (98%): Toxic if swallowed [Danger Acute toxicity, oral]

H340 (20%): May cause genetic defects [Danger Germ cell mutagenicity]

Documented Uses

Investigated for the treatment of cancer.
Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.
Compounds that inhibit the activity of DNA TOPOISOMERASE I.
Camptothecin binds to the topoisomerase I and DNA complex resulting in a ternary complex, stabilizing it and preventing DNA re-ligation and therefore causes DNA damage which results in apoptosis.

Synonyms

camptothecin; Camptothecine; 7689-03-4; (S)-(+)-Camptothecin; (+)-Camptothecin; d-Camptothecin; 20(S)-Camptothecine; (+)-Camptothecine; 21,22-Secocamptothecin-21-oic acid lactone; NSC94600; NSC-94600; DTXSID0030956; (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; XT3Z54Z28A; CHEBI:27656; 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (S)-

Frequently Asked Questions

What are the CAS number and molecular formula of Camptothecin?

CAS 7689-03-4; molecular formula C20H16N2O4; molecular weight — g/mol.

What other names is Camptothecin known by?

camptothecin, Camptothecine, 7689-03-4, (S)-(+)-Camptothecin, (+)-Camptothecin, d-Camptothecin.

Is Camptothecin classified as hazardous?

Hazard statements reported: H301, H340.

What are the key physical properties of Camptothecin?

Melting Point: 275-277 °C; LogP: 1.74.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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