卡贝缩宫素

Description

Carbetocin · CAS 37025-55-1 · C45H69N11O12S. UNII 88TWF8015Y. Solubility: 2.65e-02 g/L; LogP: -2.

Identification

CAS Registry Number	37025-55-1
PubChem CID	16681432
Molecular formula	C45H69N11O12S
IUPAC name	(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-methoxyphenyl)methyl]-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]pyrrolidine-2-carboxamide
UNII (FDA)	88TWF8015Y

Computed Descriptors

Molecular Weight	988.2
XLogP3	-1.1
Hydrogen Bond Donor Count	10
Hydrogen Bond Acceptor Count	13
Rotatable Bond Count	18
Exact Mass	987.48478785
Monoisotopic Mass	987.48478785
Topological Polar Surface Area	388
Heavy Atom Count	69
Formal Charge	0

Physical & Chemical Properties

Solubility	2.65e-02 g/L
LogP	-2

Physical description & handling notes

• Solid
• Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is sold under the trade name Duratocin. It is an analogue of oxytocin, and its action is similar to that of oxytocin; it causes contraction of the uterus.

GHS Hazard Classification

Reported hazard statements	H312, H332 (100%), H317 (100%), H361 (100%)

Documented Uses

• Used to control postpartum hemorrhage and bleeding after giving birth.
• Parenteral - General injections - IV: 100 µg per mL (heat stable)
• Dosage forms of a drug that act over a period of time by controlled-release processes or technology.
• Drugs that stimulate contraction of the myometrium. They are used to induce LABOR, OBSTETRIC at term, to prevent or control postpartum or postabortion hemorrhage, and to assess fetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (ABORTIFACIENTS). Oxytocics used clinically include the neurohypophyseal hormone OXYTOCIN and certain prostaglandins and ergot alkaloids. (From AMA Drug Evaluations, 1994, p1157)
• H - Systemic hormonal preparations, excl. sex hormones and insulins
• H01 - Pituitary and hypothalamic hormones and analogues

Synonyms

Carbetocin; 37025-55-1; Pabal; Carbetocino; Carbetocinum; carbetocine; Carbetocina; deamino-2-O-methyltyrosine-1-carbaoxytocin; LV-101; CHEBI:59204; DTXSID90897527; 88TWF8015Y; 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin; 1-Butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocin; FE-992097; 1-Carbaoxytocin, 1-butanoic acid-2-(O-methyl-L-tyrosine)-

Frequently Asked Questions

What are the CAS number and molecular formula of Carbetocin?

CAS 37025-55-1; molecular formula C45H69N11O12S; molecular weight — g/mol.

What other names is Carbetocin known by?

Carbetocin, 37025-55-1, Pabal, Carbetocino, Carbetocinum, carbetocine.

Is Carbetocin classified as hazardous?

Hazard statements reported: H312, H332, H317, H361.

What are the key physical properties of Carbetocin?

Solubility: 2.65e-02 g/L; LogP: -2.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.