头孢噻肟

Description

Cefotaxime · CAS 63527-52-6 · C16H17N5O7S2. UNII N2GI8B1GK7. Solubility: 1.46e-01 g/L; LogP: -0.5; LogP: -0.13.

Identification

CAS Registry Number	63527-52-6
PubChem CID	5742673
Molecular formula	C16H17N5O7S2
IUPAC name	(6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
UNII (FDA)	N2GI8B1GK7

Computed Descriptors

Molecular Weight	455.5
XLogP3	-1.4
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	8
Exact Mass	455.05694025
Monoisotopic Mass	455.05694025
Topological Polar Surface Area	227
Heavy Atom Count	30
Formal Charge	0

Physical & Chemical Properties

Solubility	1.46e-01 g/L
LogP	-0.5
LogP	-0.13

Physical description & handling notes

• Solid
• Soluble

GHS Hazard Classification

Reported hazard statements	H315 (58.8%), H317 (100%), H319 (58.8%), H334 (100%), H335 (58.8%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >1000
• Use (kg; exact) in Germany (2009): 2035
• Consumption (g per capita; approx.) in Germany (2009): 0.0122
• Consumption (g per capita; exact) in Germany (2009): 0.0249
• Used to treat gonorrhoea, meningitis, and severe infections including infections of the kidney (pyelonephritis) and urinary system. Also used before an operation to prevent infection after surgery.
• Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antibacterial Agents; Cephalosporins

Synonyms

cefotaxime; 63527-52-6; Cephotaxime; Cefotaxima; Cefotaximum; Cefotaxim Hikma; CHEBI:204928; N2GI8B1GK7; DTXSID6022761; Cefotaxim; Cephotaxim; Klaforan; Primafen; RefChem:54734; J01DA10; DTXCID501476108

Frequently Asked Questions

What are the CAS number and molecular formula of Cefotaxime?

CAS 63527-52-6; molecular formula C16H17N5O7S2; molecular weight — g/mol.

What other names is Cefotaxime known by?

cefotaxime, 63527-52-6, Cephotaxime, Cefotaxima, Cefotaximum, Cefotaxim Hikma.

Is Cefotaxime classified as hazardous?

Hazard statements reported: H315, H317, H319, H334, H335.

What are the key physical properties of Cefotaxime?

Solubility: 1.46e-01 g/L; LogP: -0.5; LogP: -0.13.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.