西诺贝酯

Description

Cenobamate · CAS 913088-80-9 · C10H10ClN5O2. UNII P85X70RZWS. Solubility: 1.7mg/mL; LogP: 0.456.

Identification

CAS Registry Number	913088-80-9
PubChem CID	11962412
Molecular formula	C10H10ClN5O2
IUPAC name	[(1R)-1-(2-chlorophenyl)-2-(tetrazol-2-yl)ethyl] carbamate
UNII (FDA)	P85X70RZWS

Computed Descriptors

Molecular Weight	267.67
XLogP3	1.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	267.0523023
Monoisotopic Mass	267.0523023
Topological Polar Surface Area	95.9
Heavy Atom Count	18
Formal Charge	0

Physical & Chemical Properties

Solubility	1.7mg/mL
LogP	0.456

GHS Hazard Classification

Reported hazard statements	H371 (100%), H373 (100%)

Documented Uses

• Cenobamate is indicated for the treatment of partial onset seizures in adults.
• Cenobamate is a tetrazole carbamate anticonvulsant used as therapy of partial onset seizures in adults. Cenobamate is associated with a low-to-moderate rate of serum aminotransferase elevations during therapy and has been linked to cases of clinically apparent liver injury usually in the context of a multiorgan hypersensitivity syndrome such as drug reaction with eosinophilia and systemic symptoms (DRESS).
• Breast Feeding; Lactation; Milk, Human; Anticonvulsants
• [(1R)-1-(2-chlorophenyl)-2-(tetrazol-2-yl)ethyl] carbamate|2H-tetrazole-2-ethanol|alpha-(2-chlorophenyl)-|carbamate (ester)|(alphaR)-|carbamic acid (R)-(+)-1-(2-chlorophenyl)-2-(2H-tetrazol-2-yl)ethyl ester
• Schedule V - Substances in the DEA Schedule V have a low potential for abuse relative to substances listed in Schedule IV and consist primarily of preparations containing limited quantities of certain narcotics.
• Avoid alcohol. Alcohol may increase somnolence and sedation.

Synonyms

Cenobamate; 913088-80-9; Xcopri; YKP-3089; YKP3089; Cenobamato; P85X70RZWS; [(1R)-1-(2-chlorophenyl)-2-(tetrazol-2-yl)ethyl] Carbamate; Carbamic acid (R)-(+)-1-(2-chlorophenyl)-2-(2H-tetrazol-2-yl)ethyl ester; DTXSID001027948; 2H-Tetrazole-2-ethanol, alpha-(2-chlorophenyl)-, carbamate (ester), (alphaR)-; (1R)-1-(2-chlorophenyl)-2-(2H-1,2,3,4-tetrazol-2-yl)ethyl carbamate; 2H-Tetrazole-2-ethanol, alpha-(2-chlorophenyl)-, 2-carbamate, (alphaR)-; Cenobamatum; ((1R)-1-(2-chlorophenyl)-2-(tetrazol-2-yl)ethyl) carbamate; Xcopri Titration Pack

Frequently Asked Questions

What are the CAS number and molecular formula of Cenobamate?

CAS 913088-80-9; molecular formula C10H10ClN5O2; molecular weight — g/mol.

What other names is Cenobamate known by?

Cenobamate, 913088-80-9, Xcopri, YKP-3089, YKP3089, Cenobamato.

Is Cenobamate classified as hazardous?

Hazard statements reported: H371, H373.

What are the key physical properties of Cenobamate?

Solubility: 1.7mg/mL; LogP: 0.456.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.