氯苯甘醚氨基甲酸酯

Description

chlorphenesin carbamate · CAS 886-74-8 · C10H12ClNO4. UNII 57U5YI11WP. Melting Point: 89-91 °C.

Identification

CAS Registry Number	886-74-8
PubChem CID	2724
Molecular formula	C10H12ClNO4
IUPAC name	[3-(4-chlorophenoxy)-2-hydroxypropyl] carbamate
UNII (FDA)	57U5YI11WP

Computed Descriptors

Molecular Weight	245.66
XLogP3	1.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Exact Mass	245.0454856
Monoisotopic Mass	245.0454856
Topological Polar Surface Area	81.8
Heavy Atom Count	16
Formal Charge	0

Physical & Chemical Properties

Melting Point	89-91 °C

Physical description & handling notes

• CRYSTALS FROM BENZENE + TOLUENE
• WHITE TO OFF-WHITE POWDER
• ODORLESS
• PRACTICALLY TASTELESS
• READILY SOL IN 95% ETHANOL, ACETONE, ETHYL ACETATE; FAIRLY READILY SOL IN DIOXANE; ALMOST INSOL IN COLD WATER, BENZENE, CYCLOHEXANE
• SLIGHTLY SOL IN CHLOROFORM

Documented Uses

• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• ADDITION OF P-CHLOROPHENOL TO 2,3-EPOXY-1-PROPANOL IN THE PRESENCE OF A TERTIARY AMINE CATALYST FOLLOWED BY TREATMENT OF THE RESULTING 3-(P-CHLOROPHENOXY)-1,2-PROPANEDIOL WITH CARBAMOYL CHLORIDE
• COLLINS, MATTHEWS; PARKER, US PATENTS 3,161,567; 3,214,336 (1964, 1965, BOTH TO UPJOHN).
• CHLOROPHENOL IS CAUSED TO UNDERGO ADDITION TO GLYCIDOL (2,3-EPOXY-1-PROPANOL) BY CATALYTIC INFLUENCE OF TERTIARY AMINE TO FORM 3-(P-CHLOROPHENOXY)-1,2-PROPANEDIOL & 1-HYDROXY GROUP IS THEN ESTERIFIED BY REACTION WITH CARBAMOYL CHLORIDE.
• PROBABLY 100% AS SKELETAL MUSCLE RELAXANT (1975)
• (1972) PROBABLY GREATER THAN 4.54X10+5 GRAMS

Synonyms

CHLORPHENESIN CARBAMATE; 886-74-8; Maolate; Rinlaxer; 3-(4-Chlorophenoxy)-2-hydroxypropyl carbamate; 3-(p-Chlorophenoxy)-1,2-propanediol 1-carbamate; 3-(p-Chlorophenoxy)-2-hydroxypropyl carbamate; 3-(4-Chlorophenoxy)-1,2-propanediol-1-carbamate; DTXSID5022803; U-19,646; 3-(p-Chlorophenoxy)-1,2-propanediol-1-carbamate; U 19646; 1,2-Propanediol, 3-(p-chlorophenoxy)-, 1-carbamate; NSC-82943; carbamic acid 3-(p-chlorophenoxy)-2-hydroxypropyl ester; 57U5YI11WP

Frequently Asked Questions

What are the CAS number and molecular formula of chlorphenesin carbamate?

CAS 886-74-8; molecular formula C10H12ClNO4; molecular weight — g/mol.

What other names is chlorphenesin carbamate known by?

CHLORPHENESIN CARBAMATE, 886-74-8, Maolate, Rinlaxer, 3-(4-Chlorophenoxy)-2-hydroxypropyl carbamate, 3-(p-Chlorophenoxy)-1,2-propanediol 1-carbamate.

What are the key physical properties of chlorphenesin carbamate?

Melting Point: 89-91 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.