西尼地平

Description

Cilnidipine · CAS 132203-70-4 · C27H28N2O7. UNII 97T5AZ1JIP. Boiling Point: 653ºC; Melting Point: 110ºC; LogP: 4.7.

Identification

CAS Registry Number	132203-70-4
PubChem CID	5282138
Molecular formula	C27H28N2O7
IUPAC name	3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
UNII (FDA)	97T5AZ1JIP

Computed Descriptors

Molecular Weight	492.5
XLogP3	4.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	11
Exact Mass	492.18965124
Monoisotopic Mass	492.18965124
Topological Polar Surface Area	120
Heavy Atom Count	36
Formal Charge	0

Physical & Chemical Properties

Boiling Point	653ºC
Melting Point	110ºC
LogP	4.7
Dissociation Constants	11.39

Physical description & handling notes

• Insoluble
• Administration of cilnidipine has been shown to present an antisympathetic profile in vitro and in vivo. It decreases blood pressure safely and effectively without excessive blood pressure reduction or tachycardia.

GHS Hazard Classification

Reported hazard statements	H318 (97.4%)

Documented Uses

• A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
• C08C - Selective calcium channel blockers with mainly vascular effects
• C08CA - Dihydropyridine derivatives
• QC08 - Calcium channel blockers
• QC08C - Selective calcium channel blockers with mainly vascular effects
• QC08CA - Dihydropyridine derivatives

Synonyms

cilnidipine; 132203-70-4; Atelec; Cinalong; Siscard; FRC-8653; DTXSID0046309; cilnidipino; 97T5AZ1JIP; CHEBI:31399; DTXCID8026309; cilnidipinum; RefChem:5688; 2-methoxyethyl-3-phenyl-2-propen-1-yl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate; C08CA14; 3-cinnamyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Frequently Asked Questions

What are the CAS number and molecular formula of Cilnidipine?

CAS 132203-70-4; molecular formula C27H28N2O7; molecular weight — g/mol.

What other names is Cilnidipine known by?

cilnidipine, 132203-70-4, Atelec, Cinalong, Siscard, FRC-8653.

Is Cilnidipine classified as hazardous?

Hazard statements reported: H318.

What are the key physical properties of Cilnidipine?

Boiling Point: 653ºC; Melting Point: 110ºC; LogP: 4.7; Dissociation Constants: 11.39.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.