clobetasone butyrate

Description

clobetasone butyrate · CAS 25122-57-0 · C26H32ClFO5. UNII 8U0H6XI6EO. LogP: 3.76.

Identification

CAS Registry Number	25122-57-0
PubChem CID	71386
Molecular formula	C26H32ClFO5
IUPAC name	[(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-10,13,16-trimethyl-3,11-dioxo-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] butanoate
UNII (FDA)	8U0H6XI6EO

Computed Descriptors

Molecular Weight	479.0
XLogP3	3.8
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	478.1922300
Monoisotopic Mass	478.1922300
Topological Polar Surface Area	77.5
Heavy Atom Count	33
Formal Charge	0

Physical & Chemical Properties

LogP	3.76

GHS Hazard Classification

Reported hazard statements	H351 (86.4%)

Documented Uses

• Substances that reduce or suppress INFLAMMATION.
• A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.

Synonyms

clobetasone butyrate; 25122-57-0; Clobetasone 17-butyrate; Eumovate; Emovate; Kindavate; Molivate; Cloptison; DTXSID3046823; CCI 5537; GR 2/1214; 8U0H6XI6EO; SN 203; DTXCID1026823; CCI-5537; Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16-beta)-

Frequently Asked Questions

What are the CAS number and molecular formula of clobetasone butyrate?

CAS 25122-57-0; molecular formula C26H32ClFO5; molecular weight — g/mol.

What other names is clobetasone butyrate known by?

clobetasone butyrate, 25122-57-0, Clobetasone 17-butyrate, Eumovate, Emovate, Kindavate.

Is clobetasone butyrate classified as hazardous?

Hazard statements reported: H351.

What are the key physical properties of clobetasone butyrate?

LogP: 3.76.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.