clotrimazole crystalline

Description

clotrimazole crystalline · CAS 23593-75-1 · C22H17ClN2. UNII G07GZ97H65. Melting Point: 148; Melting Point: 147-149 °C; Melting Point: 148 °C.

Identification

CAS Registry Number	23593-75-1
PubChem CID	2812
Molecular formula	C22H17ClN2
IUPAC name	1-[(2-chlorophenyl)-diphenylmethyl]imidazole
UNII (FDA)	G07GZ97H65

Computed Descriptors

Molecular Weight	344.8
XLogP3	5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	4
Exact Mass	344.1080262
Monoisotopic Mass	344.1080262
Topological Polar Surface Area	17.8
Heavy Atom Count	25
Formal Charge	0

Physical & Chemical Properties

Melting Point	148
Melting Point	147-149 °C
Melting Point	148 °C
Solubility	0.49
LogP	6.1
LogP	4.75
Dissociation Constants	4.1
Formulations/Preparations	Mycelex 1% cream

Physical description & handling notes

• Solid
• Crystals
• White to pale yellow crystalline powder
• Odorless
• SOL IN ACETONE, CHLOROFORM, ETHYL ACETATE; SLIGHTLY SOL IN WATER, BENZENE, TOLUENE
• Freely soluble in alcohol; soluble in polyethylene glycol 400

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Antimicrobial; Antidandruff
GHS notification summary	1.5% (3 / 196)

GHS Hazard Classification

GHS notification summary	1.5% (3 / 196)
Reported hazard statements	H302 (96.9%), H311 (17.9%), H315 (65.3%), H319 (74.5%), H361 (17.9%), H373 (17.9%), H400 (71.4%), H410 (72.4%)

Documented Uses

• Use (kg) in Switzerland (2009): >100
• Use (kg; approx.) in Germany (2009): >2500
• Consumption (g per capita) in Switzerland (2009): 0.013
• Consumption (g per capita; approx.) in Germany (2009): 0.031
• Consumption (g per capita) in the USA (2002): 0.0036
• For the local treatment of oropharyngeal candidiasis and vaginal yeast infections, also used in fungal infections of the skin such as ringworm, athlete's foot, and jock itch.

Synonyms

clotrimazole; 23593-75-1; Lotrimin; Canesten; Mycosporin; Mycelex; Clotrimazol; Empecid; Mykosporin; Gyne lotrimin; Chlotrimazole; Trimysten; Gyne-Lotrimin; Mycelex G; Rimazole; Tibatin

Frequently Asked Questions

What are the CAS number and molecular formula of clotrimazole crystalline?

CAS 23593-75-1; molecular formula C22H17ClN2; molecular weight — g/mol.

What other names is clotrimazole crystalline known by?

clotrimazole, 23593-75-1, Lotrimin, Canesten, Mycosporin, Mycelex.

What is the regulatory status of clotrimazole crystalline?

Documented regulatory listings: CIR / INCI: Antimicrobial; Antidandruff.

Is clotrimazole crystalline classified as hazardous?

1.5% of GHS notifications report no hazard classification (3 of 196).

What are the key physical properties of clotrimazole crystalline?

Melting Point: 148; Melting Point: 147-149 °C; Melting Point: 148 °C; Solubility: 0.49.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.