cytosine arabinoside hydrochloride

Description

cytosine arabinoside hydrochloride · CAS 69-74-9 · C9H13N3O5.ClH. UNII 33K3DB6591. Melting Point: 356 to 360 °F (NTP, 1992).

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Crystals (from aqueous ethanol) or fluffy white powder. (NTP, 1992)
• greater than or equal to 100 mg/mL at 63 °F (NTP, 1992)
• >42 [ug/mL] (The mean of the results at pH 7.4)

GHS Hazard Classification

Documented Uses

• For the treatment of acute non-lymphocytic leukemia, acute lymphocytic leukemia and blast phase of chronic myelocytic leukemia.
• Breast Feeding; Lactation; Milk, Human; Antimetabolites, Antineoplastic; Immunosuppressive Agents; Nucleosides
• Antimetabolites that are useful in cancer chemotherapy.
• Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
• Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.

Synonyms

CYTARABINE HYDROCHLORIDE; 69-74-9; Cytosine arabinoside hydrochloride; Cytarabine HCl; 1-beta-D-Arabinofuranosylcytosine hydrochloride; Cytosar hydrochloride; Spongocytidine hydrochloride; Arabitin hydrochloride; Aracytidine hydrochloride; U-19920A; Iretin; DTXSID5024891; Aracytin hydrochloride; NSC-63878; 33K3DB6591; 1-beta-D-Arabinofuranosylcytosine monohydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of cytosine arabinoside hydrochloride?

CAS 69-74-9; molecular formula C9H13N3O5.ClH; molecular weight — g/mol.

What other names is cytosine arabinoside hydrochloride known by?

CYTARABINE HYDROCHLORIDE, 69-74-9, Cytosine arabinoside hydrochloride, Cytarabine HCl, 1-beta-D-Arabinofuranosylcytosine hydrochloride, Cytosar hydrochloride.

Is cytosine arabinoside hydrochloride classified as hazardous?

Hazard statements reported: H317, H319, H341, H361.

What are the key physical properties of cytosine arabinoside hydrochloride?

Melting Point: 356 to 360 °F (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.