D-Menthol

Description

D-Menthol · CAS 15356-60-2 · C10H20O. UNII C6B1OE8P3W. Boiling Point: 421 °F at 760 mmHg (NTP, 1992); Boiling Point: 212 °C ((-)-isomer 216.5); Melting Point: 100 °F (NTP, 1992).

Identification

CAS Registry Number	15356-60-2
PubChem CID	165675
Molecular formula	C10H20O
IUPAC name	(1S,2R,5S)-5-methyl-2-propan-2-ylcyclohexan-1-ol
UNII (FDA)	C6B1OE8P3W
FEMA number	2665
JECFA number	427

Computed Descriptors

Molecular Weight	156.26
XLogP3	3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Exact Mass	156.151415257
Monoisotopic Mass	156.151415257
Topological Polar Surface Area	20.2
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

Boiling Point	421 °F at 760 mmHg (NTP, 1992)
Boiling Point	212 °C ((-)-isomer 216.5)
Melting Point	100 °F (NTP, 1992)
Flash Point	196 °F (NTP, 1992)
Density	0.901 (20 °C); 0.891 (30 °C)
Vapor Pressure	0.8 [mmHg]
Refractive Index	1.461

Physical description & handling notes

• D,l-menthol is a white crystalline solid with a peppermint odor and taste. (NTP, 1992)
• Large Crystals
• Other Solid; Liquid
• White solid with a minty odor; [OECD SIDS: IUCLID Data Set] White crystalline solid; [Sigma-Aldrich MSDS]
• colourless, hexagonal crystals, usually needle-like; fused masses or crystalline powder with a pleasant, peppermint-like odour
• less than 1 mg/mL at 70 °F (NTP, 1992)

Regulatory Status

Regulatory & Food Contact	Flavoring Agents Mint, Cool CIR / INCI: Cosmetics ingredient -> Buffering/pH Adjusting; Conditioning/Emollient; Flavor; Fragrance; Other (Specify)
GHS notification summary	0.1% (1 / 1451)

GHS Hazard Classification

GHS notification summary	0.1% (1 / 1451)
Reported hazard statements	H315, H302 (10.9%), H314 (10.9%), H318 (13.5%), H319 (12.6%), H335 (13.5%), H373 (10.9%), H400 (10.9%)

Documented Uses

• Pure form used only for scientific purposes; [OECD SIDS: IUCLID Data Set]
• Flavoring Agents -> JECFA Flavorings Index
• Cosmetics product ingredient: Menthol (dl-menthol; l-menthol; d-menthol)
• Menthol is a fragrance allergen. Fragrance allergens are hazardous only to individuals who suffer from fragrance allergies. The Cosmetic Fragrance and Flavor Ingredient Right to Know Act of 2020 requires fragrance allergens included in Annex III of the EU Cosmetics Regulation No. 1223/2009 be reported to the California Department of Public Health. Fragrance allergens are only required to be reported if present in a rinse-off cosmetic product at a concentration at or above 0.01 percent (100 parts per million) or in
• For more information, you can visit the fragrance allergens webpage on the California Safe Cosmetics Program website:

Synonyms

(+)-Menthol; 15356-60-2; d-Menthol; (1S,2R,5S)-(+)-Menthol; (1S,2R,5S)-Menthol; (1S,2R,5S)-2-Isopropyl-5-methylcyclohexanol; Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1S,2R,5S)-; Menthol, (+)-; DTXSID8029733; C6B1OE8P3W; Menthol, (1S,3S,4R)-(+)-; (+)-(1S,2R,5S)-menthol; (+)-(1S,3S,4R)-menthol; EINECS 239-387-8; MENTHOL, D-; DTXCID409733

Frequently Asked Questions

What are the CAS number and molecular formula of D-Menthol?

CAS 15356-60-2; molecular formula C10H20O; molecular weight — g/mol.

What other names is D-Menthol known by?

(+)-Menthol, 15356-60-2, d-Menthol, (1S,2R,5S)-(+)-Menthol, (1S,2R,5S)-Menthol, (1S,2R,5S)-2-Isopropyl-5-methylcyclohexanol.

What is the regulatory status of D-Menthol?

Documented regulatory listings: Flavoring Agents; Mint, Cool; CIR / INCI: Cosmetics ingredient -> Buffering/pH Adjusting; Conditioning/Emollient; Flavor; Fragrance; Other (Specify).

Is D-Menthol classified as hazardous?

0.1% of GHS notifications report no hazard classification (1 of 1451).

What are the key physical properties of D-Menthol?

Boiling Point: 421 °F at 760 mmHg (NTP, 1992); Boiling Point: 212 °C ((-)-isomer 216.5); Melting Point: 100 °F (NTP, 1992); Flash Point: 196 °F (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.