达托霉素

Description

Daptomycin · CAS 103060-53-3 · C72H101N17O26. UNII NWQ5N31VKK.

Identification

CAS Registry Number	103060-53-3
PubChem CID	21585658
Molecular formula	C72H101N17O26
UNII (FDA)	NWQ5N31VKK

Computed Descriptors

Molecular Weight	1620.7
XLogP3	-5.1
Hydrogen Bond Donor Count	22
Hydrogen Bond Acceptor Count	28
Rotatable Bond Count	35
Exact Mass	1619.71036639
Monoisotopic Mass	1619.71036639
Topological Polar Surface Area	702
Heavy Atom Count	115
Formal Charge	0

Regulatory Status

GHS notification summary	2.4% (1 / 42)

GHS Hazard Classification

GHS notification summary	2.4% (1 / 42)
Reported hazard statements	H373 (85.7%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >10
• Consumption (g per capita; approx.) in Germany (2009): 0.000122
• Daptomycin is a cyclic lipopeptide antibiotic derived from the organism Streptomyces roseosporus. Daptomycin treats various bacterial infections caused by gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci (VRE). Daptomycin is prescribed for various FDA-approved and off-label clinical uses.
• Daptomycin is an intravenously administered, broad spectrum antibiotic used to treat complex skin and tissue infections, endocarditis and bacteremia. Daptomycin is associated with a low to modest rate of serum enzyme elevations during therapy, but is a very rare cause of clinically apparent liver injury.
• Breast Feeding; Lactation; Anti-Infective Agents; Antibacterial Agents; Peptides, Cyclic; Lipopeptides
• Substances that inhibit the growth or reproduction of BACTERIA.

Synonyms

DAPTOMYCIN; Cidecin; 103060-53-3; Cubicin; Daptomycinum; Daptomycine; Dapcin; Cubicin Rf; NWQ5N31VKK; DAPZURA RT; LY-146032; DTXSID1041009; LY146032; LY 146032; LY-164032; CHEBI:600103

Frequently Asked Questions

What are the CAS number and molecular formula of Daptomycin?

CAS 103060-53-3; molecular formula C72H101N17O26; molecular weight — g/mol.

What other names is Daptomycin known by?

DAPTOMYCIN, Cidecin, 103060-53-3, Cubicin, Daptomycinum, Daptomycine.

Is Daptomycin classified as hazardous?

2.4% of GHS notifications report no hazard classification (1 of 42).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.