地夫可特

Name: 地夫可特
Brand: 济南圣和化工有限公司

CAS 14484-47-0C25H31NO6MW 441.5

地夫可特，CAS 登记号 14484-47-0，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于医药中间体及原料药。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号14484-47-0

分子式C25H31NO6

分子量441.5

熔点>215 C

LogP2.4

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域医药中间体及原料药

类别医药中间体及原料药

用途与场景

医药中间体及原料药

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

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常见问题

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主要涉及医药中间体及原料药。

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PubChem 公开数据

Description

Deflazacort · CAS 14484-47-0 · C25H31NO6. UNII KR5YZ6AE4B. Melting Point: >215 C; Solubility: 108; LogP: 2.4.

Identification

CAS Registry Number	14484-47-0
PubChem CID	189821
Molecular formula	C25H31NO6
IUPAC name	[2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-6,9,13-trimethyl-16-oxo-5-oxa-7-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-6,14,17-trien-8-yl]-2-oxoethyl] acetate
UNII (FDA)	KR5YZ6AE4B

Computed Descriptors

Molecular Weight	441.5
XLogP3	2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	4
Exact Mass	441.21513771
Monoisotopic Mass	441.21513771
Topological Polar Surface Area	102
Heavy Atom Count	32
Formal Charge	0

Physical & Chemical Properties

Melting Point	>215 C
Solubility	108
LogP	2.4
Dissociation Constants	5.52

Physical description & handling notes

204.8 Å² [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID9020378]
206.7 Å² [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID9020378]
213.4 Å² [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID9020378]
205.2 Å² [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID9020378]

GHS Hazard Classification

Reported hazard statements	H360 (77.4%), H361 (16.1%), H373 (93.5%)

H360 (77.4%): May damage fertility or the unborn child [Danger Reproductive toxicity]

H361 (16.1%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

Deflazacort is indicated for the treatment of Duchenne Muscular Dystrophy (DMD) in patients 2 years of age and older.
Breast Feeding; Lactation; Corticosteroids, Systemic; Glucocorticoids; Anti-Inflammatory Agents;
Deflazacort (Class: Other Substances, Added Date: 08-2025)
Avoid grapefruit products. Grapefruit inhibits CYP3A metabolism, which may increase the serum concentration of deflazacort.
Avoid St. John's Wort. This herb induces CYP3A metabolism and may reduce serum levels of deflazacort.
Take with or without food. The tablets may be crushed and mixed with applesauce and consumed immediately.

Synonyms

DEFLAZACORT; 14484-47-0; Emflaza; Deflazacortum; DTXSID9020378; MDL 458; DL-458IT; L-5458; MDL-458; KR5YZ6AE4B; MDL458; DTXCID10378; 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 21-(acetyloxy)-11-hydroxy-2'-methyl-, (11beta,16beta)-; 5'H-Pregna-1,4-dieno(17,16-d)oxazole-3,20-dione, 21-(acetyloxy)-11-hydroxy-2'-methyl-, (11beta,16beta)-; Deflazacort Oral; RefChem:56797

Frequently Asked Questions

What are the CAS number and molecular formula of Deflazacort?

CAS 14484-47-0; molecular formula C25H31NO6; molecular weight — g/mol.

What other names is Deflazacort known by?

DEFLAZACORT, 14484-47-0, Emflaza, Deflazacortum, DTXSID9020378, MDL 458.

Is Deflazacort classified as hazardous?

Hazard statements reported: H360, H361, H373.

What are the key physical properties of Deflazacort?

Melting Point: >215 C; Solubility: 108; LogP: 2.4; Dissociation Constants: 5.52.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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