地拉普利

Description

Delapril · CAS 83435-66-9 · C26H32N2O5. UNII W77UAL9THI.

Identification

CAS Registry Number	83435-66-9
PubChem CID	5362116
Molecular formula	C26H32N2O5
IUPAC name	2-[2,3-dihydro-1H-inden-2-yl-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]amino]acetic acid
UNII (FDA)	W77UAL9THI

Computed Descriptors

Molecular Weight	452.5
XLogP3	1.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	12
Exact Mass	452.23112213
Monoisotopic Mass	452.23112213
Topological Polar Surface Area	95.9
Heavy Atom Count	33
Formal Charge	0

Documented Uses

• Use (kg; approx.) in Germany (2009): >25
• Consumption (g per capita; approx.) in Germany (2009): 0.000305
• A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• C09 - Agents acting on the renin-angiotensin system
• QC09 - Agents acting on the renin-angiotensin system

Synonyms

DELAPRIL; 83435-66-9; Delaprilum; W77UAL9THI; CV-3317; DTXSID101016742; Glycine, N-(2,3-dihydro-1H-inden-2-yl)-N-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-, (S)-; derapril; RefChem:131598; C09AA12; DTXCID501474926; N-(2,3-dihydro-1H-inden-2-yl)-N-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)alanyl)glycine; Delapril [INN]; Alindapril; Delaprilum [Latin]; NCGC00181755-01

Frequently Asked Questions

What are the CAS number and molecular formula of Delapril?

CAS 83435-66-9; molecular formula C26H32N2O5; molecular weight — g/mol.

What other names is Delapril known by?

DELAPRIL, 83435-66-9, Delaprilum, W77UAL9THI, CV-3317, DTXSID101016742.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.