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desipramine hydrochloride

CAS 58-28-6C18H23ClN2MW 302.8

desipramine hydrochloride (CAS No. 58-28-6) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number58-28-6
Molecular FormulaC18H23ClN2
Molecular Weight302.8
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of desipramine hydrochloride?

The CAS number of desipramine hydrochloride is 58-28-6.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of desipramine hydrochloride?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy desipramine hydrochloride or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

desipramine hydrochloride · CAS 58-28-6 · C18H23ClN2. UNII 1Y58DO4MY1.

Identification

CAS Registry Number58-28-6
PubChem CID65327
Molecular formulaC18H23ClN2
IUPAC name3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine;hydrochloride
UNII (FDA)1Y58DO4MY1

Computed Descriptors

Molecular Weight302.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Exact Mass302.1549764
Monoisotopic Mass302.1549764
Topological Polar Surface Area15.3
Heavy Atom Count21
Formal Charge0
Complexity267

Physical description & handling notes

  • >45.4 [ug/mL] (The mean of the results at pH 7.4)
  • 162.1 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statementsH302 (97.9%), H315 (89.4%), H317 (89.4%), H319 (89.4%), H334 (89.4%), H335 (89.4%), H336 (10.6%)

H302 (97.9%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (89.4%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

  • Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
  • Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
  • Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.

Synonyms

Desipramine hydrochloride; 58-28-6; Desipramine Hcl; DMI hydrochloride; RMI 9,384A; Desmethylimipramine chloride; Desimipramine, hydrochloride; NSC-114901; Desipramine monohydrochloride; EX 4355; Demethylimipramine hydrochloride; Imipraminedemethyl hydrochloride; G-35020; Desmethylimipramine hydrochloride; JB-8181; Desmethylimipramine monohydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of desipramine hydrochloride?

CAS 58-28-6; molecular formula C18H23ClN2; molecular weight — g/mol.

What other names is desipramine hydrochloride known by?

Desipramine hydrochloride, 58-28-6, Desipramine Hcl, DMI hydrochloride, RMI 9,384A, Desmethylimipramine chloride.

Is desipramine hydrochloride classified as hazardous?

Hazard statements reported: H302, H315, H317, H319, H334.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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