马来酸右氯苯那敏

Description

Dexchlorpheniramine Maleate · CAS 2438-32-6 · C16H19ClN2.C4H4O4. UNII V1Q0O9OJ9Z. Melting Point: 266 to 275 °F (NTP, 1992); Solubility: 10 to 50 mg/mL at 70 °F (NTP, 1992).

Identification

CAS Registry Number	2438-32-6
PubChem CID	5281068
Molecular formula	C16H19ClN2.C4H4O4
IUPAC name	(Z)-but-2-enedioic acid;3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
UNII (FDA)	V1Q0O9OJ9Z

Computed Descriptors

Molecular Weight	390.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	7
Exact Mass	390.1346349
Monoisotopic Mass	390.1346349
Topological Polar Surface Area	90.7
Heavy Atom Count	27
Formal Charge	0
Complexity	368

Physical & Chemical Properties

Melting Point	266 to 275 °F (NTP, 1992)
Solubility	10 to 50 mg/mL at 70 °F (NTP, 1992)

Physical description & handling notes

• Chlorpheniramine maleate appears as odorless white crystalline solid or white powder with a bitter taste. pH (2% aqueous solution) 5. pH (1% aqueous solution) 4-5. (NTP, 1992)

Regulatory Status

GHS notification summary	0.8% (2 / 241)

GHS Hazard Classification

GHS notification summary	0.8% (2 / 241)
Reported hazard statements	H301 (87.6%), H302 (11.2%), H311 (32.8%), H314 (14.9%), H318 (15.8%), H336 (16.2%), H373 (15.4%), H361

Documented Uses

• Used used in the prevention of the symptoms of allergic conditions such as rhinitis, urticaria, allergy, common cold, asthma and hay fever.
• 2-Pyridinepropanamine, .gamma.-(4-chlorophenyl)-N,N-dimethyl-, (2Z)-2-butenedioate (1:1): ACTIVE
• Breast Feeding; Lactation; Milk, Human; Antihistamines; Antipruritics
• Agents, usually topical, that relieve itching (pruritus).
• Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475)
• Histamine-1 Receptor Antagonist [EPC]; Histamine H1 Receptor Antagonists [MoA]

Synonyms

Chlorpheniramine maleate; 113-92-8; Neorestamin; Synistamin; Antagonate; Allerclor; Kloromin; Phenetron; Allergin; Chlormene; Pyridamal; Alunex; Ibioton; Lorphen; Piriex; C-Meton

Frequently Asked Questions

What are the CAS number and molecular formula of Dexchlorpheniramine Maleate?

CAS 2438-32-6; molecular formula C16H19ClN2.C4H4O4; molecular weight — g/mol.

What other names is Dexchlorpheniramine Maleate known by?

Chlorpheniramine maleate, 113-92-8, Neorestamin, Synistamin, Antagonate, Allerclor.

Is Dexchlorpheniramine Maleate classified as hazardous?

0.8% of GHS notifications report no hazard classification (2 of 241).

What are the key physical properties of Dexchlorpheniramine Maleate?

Melting Point: 266 to 275 °F (NTP, 1992); Solubility: 10 to 50 mg/mL at 70 °F (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.