二苯西平

Description

dibenzepin · CAS 4498-32-2 · C18H21N3O. UNII 510SJZ1Y6L. LogP: 2.6; Dissociation Constants: 8.275.

Identification

CAS Registry Number	4498-32-2
PubChem CID	9419
Molecular formula	C18H21N3O
IUPAC name	5-[2-(dimethylamino)ethyl]-11-methylbenzo[b][1,4]benzodiazepin-6-one
UNII (FDA)	510SJZ1Y6L

Computed Descriptors

Molecular Weight	295.4
XLogP3	2.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	295.168462302
Monoisotopic Mass	295.168462302
Topological Polar Surface Area	26.8
Heavy Atom Count	22
Formal Charge	0

Physical & Chemical Properties

LogP	2.6
Dissociation Constants	8.275

Documented Uses

• Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
• N06AA - Non-selective monoamine reuptake inhibitors
• QN06AA - Non-selective monoamine reuptake inhibitors

Synonyms

Dibenzepin; 4498-32-2; Dibenzepina; Dibenzepinum; 510SJZ1Y6L; 5-[2-(dimethylamino)ethyl]-11-methylbenzo[b][1,4]benzodiazepin-6-one; DTXSID7022916; 11H-Dibenzo[b,e][1,4]diazepin-11-one, 10-[2-(dimethylamino)ethyl]-5,10-dihydro-5-methyl-; 11H-Dibenzo(b,e)(1,4)diazepin-11-one, 10-(2-(dimethylamino)ethyl)-5,10-dihydro-5-methyl-; 5-(2-(dimethylamino)ethyl)-11-methylbenzo(b)(1,4)benzodiazepin-6-one; RefChem:132799; DTXCID702916; N06AA08; Dibenzepine; 10-[2-(Dimethylamino)ethyl]-5,10-dihydro-5-methyl-11H-dibenzo[b,e][1,4]diazepin-11-one; Dibenzepin (INN)

Frequently Asked Questions

What are the CAS number and molecular formula of dibenzepin?

CAS 4498-32-2; molecular formula C18H21N3O; molecular weight — g/mol.

What other names is dibenzepin known by?

Dibenzepin, 4498-32-2, Dibenzepina, Dibenzepinum, 510SJZ1Y6L, 5-[2-(dimethylamino)ethyl]-11-methylbenzo[b][1,4]benzodiazepin-6-one.

What are the key physical properties of dibenzepin?

LogP: 2.6; Dissociation Constants: 8.275.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.