盐酸双环胺

Description

dicyclomine hydrochloride · CAS 67-92-5 · C19H35NO2. UNII 4KV4X8IF6V. Melting Point: 165-166; Solubility: 3.27e-03 g/L; LogP: 5.5.

Identification

CAS Registry Number	67-92-5
PubChem CID	3042
Molecular formula	C19H35NO2
IUPAC name	2-(diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate
UNII (FDA)	4KV4X8IF6V

Computed Descriptors

Molecular Weight	309.5
XLogP3	5.5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	8
Exact Mass	309.266779359
Monoisotopic Mass	309.266779359
Topological Polar Surface Area	29.5
Heavy Atom Count	22
Formal Charge	0

Physical & Chemical Properties

Melting Point	165-166
Solubility	3.27e-03 g/L
LogP	5.5
Other Experimental Properties	MP 164-166 °C /HYDROCHLORIDE/

Physical description & handling notes

• Solid
• SOL IN WATER ABOUT 25% /HYDROCHLORIDE/
• 1 G IN 13 ML WATER, 5 ML ALC, 2.5 ML CHLOROFORM, 770 ML ETHER; INSOL IN ALKALINE AQ MEDIUM /HCL/
• STABLE IN AIR & TO MODERATE HEAT /HYDROCHLORIDE/
• 185.38 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 179.29 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Documented Uses

• Consumption (g per capita) in the USA (2002): 0.00798
• US PATENT 2,474,796. /HYDROCHLORIDE/
• PREPD FROM 1-CYCLOHEXYLCYCLOHEXYL CYANIDE BY ALCOHOLYSIS & ESTERIFICATION... /HYDROCHLORIDE/
• [1,1'-Bicyclohexyl]-1-carboxylic acid, 2-(diethylamino)ethyl ester: INACTIVE
• Dicyclomine is indicated for the treatment of functional bowel disorder and irritable bowel syndrome.
• Dicyclomine is an anticholinergic agent used to treat gastrointestinal conditions such as acid peptic disease and irritable bowel syndrome. Dicyclomine has not been implicated in causing liver enzyme elevations or clinically apparent acute liver injury.

Synonyms

dicyclomine; Dicycloverine; Dicycloverin; 77-19-0; Diocyl; Dicicloverina; Dicycloverinum; Dicymine; 2-(diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate; DTXSID1022926; 4KV4X8IF6V; (Bicyclohexyl)-1-carboxylic acid, 2-(diethylamino)ethyl ester; [1,1'-Bicyclohexyl]-1-carboxylic acid, 2-(diethylamino)ethyl ester; 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate; (1,1'-Bicyclohexyl)-1-carboxylic acid, 2-(diethylamino)ethyl ester; 2-diethylaminoethyl 1-cyclohexylcyclohexane-1-carboxylate

Frequently Asked Questions

What are the CAS number and molecular formula of dicyclomine hydrochloride?

CAS 67-92-5; molecular formula C19H35NO2; molecular weight — g/mol.

What other names is dicyclomine hydrochloride known by?

dicyclomine, Dicycloverine, Dicycloverin, 77-19-0, Diocyl, Dicicloverina.

Is dicyclomine hydrochloride classified as hazardous?

Hazard statements reported: H302.

What are the key physical properties of dicyclomine hydrochloride?

Melting Point: 165-166; Solubility: 3.27e-03 g/L; LogP: 5.5; Other Experimental Properties: MP 164-166 °C /HYDROCHLORIDE/.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.