Dilmapimod

Name: Dilmapimod
Brand: Jinan Shenghe Chemical Co., Ltd.

CAS 444606-18-2C23H19F3N4O3MW 456.4

Dilmapimod (CAS No. 444606-18-2) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number444606-18-2

Molecular FormulaC23H19F3N4O3

Molecular Weight456.4

LogP3

Purity按批次COA提供(不公开发布)

Packaging按订单/批次确认(不公开发布)

ApplicationsPharmaceutical Intermediates & APIs

CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)

Purity按批次COA提供(不公开发布)

StorageSealed, cool and dry place

Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Dilmapimod?

The CAS number of Dilmapimod is 444606-18-2.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Dilmapimod?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Dilmapimod or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Dilmapimod · CAS 444606-18-2 · C23H19F3N4O3. UNII Q3238VQW0N.

Identification

CAS Registry Number	444606-18-2
PubChem CID	10297982
Molecular formula	C23H19F3N4O3
IUPAC name	8-(2,6-difluorophenyl)-2-(1,3-dihydroxypropan-2-ylamino)-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7-one
UNII (FDA)	Q3238VQW0N

Computed Descriptors

Molecular Weight	456.4
XLogP3	3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	6
Exact Mass	456.14092497
Monoisotopic Mass	456.14092497
Topological Polar Surface Area	98.6
Heavy Atom Count	33
Formal Charge	0

Documented Uses

Dilmapimod has been used in trials studying the treatment and diagnostic of Nerve Trauma, Inflammation, Pain, Neuropathic, Arthritis, Rheumatoid, and Coronary Heart Disease, among others.
Dilmapimod reduces the levels of proinflammatory cytokines and chemokines and reduce cellular infiltration to sites of inflammation, thereby reducing local damage. In diseases such as RA and IBD, TNFα blockade through either anti-TNFα antibodies or use of soluble TNFα receptors. Inhibition of p38α offers significant inhibition of TNFα, and cytokines such as IL-1β and IL-6, which offer additional therapeutic efficacy.

Synonyms

Dilmapimod; 444606-18-2; SB-681323; Q3238VQW0N; SB681323; DTXSID101318338; dilmapimodum; GW681323; RefChem:587981; DTXCID401748150; Dilmapimod [USAN:INN]; GW 681323; UNII-Q3238VQW0N; SB 681323; GSK 681323; SB-681323; GW 681323

Frequently Asked Questions

What are the CAS number and molecular formula of Dilmapimod?

CAS 444606-18-2; molecular formula C23H19F3N4O3; molecular weight — g/mol.

What other names is Dilmapimod known by?

Dilmapimod, 444606-18-2, SB-681323, Q3238VQW0N, SB681323, DTXSID101318338.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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