dobutamine

Description

dobutamine · CAS 34368-04-2 · C18H23NO3. UNII 3S12J47372. Melting Point: 184-186; Solubility: 1.37e-02 g/L; LogP: 3.6.

Identification

CAS Registry Number	34368-04-2
PubChem CID	36811
Molecular formula	C18H23NO3
IUPAC name	4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol
UNII (FDA)	3S12J47372

Computed Descriptors

Molecular Weight	301.4
XLogP3	3.4
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	7
Exact Mass	301.16779360
Monoisotopic Mass	301.16779360
Topological Polar Surface Area	72.7
Heavy Atom Count	22
Formal Charge	0

Physical & Chemical Properties

Melting Point	184-186
Solubility	1.37e-02 g/L
LogP	3.6

Physical description & handling notes

• Solid
• 167.13 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 165.98 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 168.2 Ų [M+H]+ [CCS Type: TW; Method: Major Mix IMS/Tof Calibration Kit (Waters)]

GHS Hazard Classification

Reported hazard statements	H302, H312, H332 (100%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >250
• Consumption (g per capita; approx.) in Germany (2009): 0.00305
• Indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.
• Breast Feeding; Lactation; Adrenergic beta-Agonists; Cardiotonic Agents; Catecholamines; Sympathomimetics
• Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
• Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.

Synonyms

dobutamine; 34368-04-2; DL-dobutamine; Dobutamina; racemic-Dobutamine; Dobutaminum; Racemic dobutamine; rac-dobutamine; Compound 81929; 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol; DTXSID3022958; 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol; COMPOUND-81929; (+-)-4-(2-((3-(p-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol; CHEBI:4670; DTXCID702958

Frequently Asked Questions

What are the CAS number and molecular formula of dobutamine?

CAS 34368-04-2; molecular formula C18H23NO3; molecular weight — g/mol.

What other names is dobutamine known by?

dobutamine, 34368-04-2, DL-dobutamine, Dobutamina, racemic-Dobutamine, Dobutaminum.

Is dobutamine classified as hazardous?

Hazard statements reported: H302, H312, H332.

What are the key physical properties of dobutamine?

Melting Point: 184-186; Solubility: 1.37e-02 g/L; LogP: 3.6.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.