dyclocaine

Description

dyclocaine · CAS 586-60-7 · C18H27NO2. UNII 078A24Q30O. Melting Point: 174-175; Solubility: 4.60e-02 g/L; LogP: 3.7.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Solid
• Soluble (HCl salt)
• 178.11 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• Dyclonine is an oral anasthetic. If substantial quantities of local anesthetics are absorbed through the mucosa, actions on the central nervous system (CNS) may cause CNS stimulation and/or CNS depression. Actions on the cardiovascular system may cause depression of cardiac conduction and excitability and, with some of these agents, peripheral vasodilation.

Documented Uses

• Used to provide topical anesthesia of accessible mucous membranes prior to examination, endoscopy or instrumentation, or other procedures involving the esophagus, larynx, mouth, pharynx or throat, respiratory tract or trachea, urinary tract, or vagina. Also used to suppress the gag reflex and/or other laryngeal and esophageal reflexes to facilitate dental examination or procedures (including oral surgery), endoscopy, or intubation. Also used for relief of canker sores, cold sores or fever blister.
• Breast Feeding; Lactation; Anesthetics, Local
• Dyclonine (Class: Other Substances, Added Date: 10-1998)
• Take separate from meals. Using Dyclonine in the mouth or for relief of ulcers in the stomach may cause numbness of the mouth, which increases the risk of biting injury. Avoid ingesting food for 60 minutes after use, or until the numbness has subsided.
• N01BX - Other local anesthetics
• QN01BX - Other local anesthetics

Synonyms

dyclonine; Dyclocaine; 586-60-7; Diclonina; Dycloninum; 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one; 4'-Butoxy-3-piperidinopropiophenone; 3-Piperidino-4'-butoxypropiophenone; 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone; 2-(1-piperidyl)ethyl p-butoxyphenyl ketone; 4-butoxy-beta-piperidinopropiophenone; 4-n-butoxy-beta-(1-piperidyl)propiophenone; 078A24Q30O; CHEBI:4724; DTXSID6047864; 1-propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl)

Frequently Asked Questions

What are the CAS number and molecular formula of dyclocaine?

CAS 586-60-7; molecular formula C18H27NO2; molecular weight — g/mol.

What other names is dyclocaine known by?

dyclonine, Dyclocaine, 586-60-7, Diclonina, Dycloninum, 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one.

What are the key physical properties of dyclocaine?

Melting Point: 174-175; Solubility: 4.60e-02 g/L; LogP: 3.7.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.