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EFAVIRENZ

CAS 154598-52-4C14H9ClF3NO2MW 315.67

EFAVIRENZ (CAS No. 154598-52-4) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number154598-52-4
Molecular FormulaC14H9ClF3NO2
Molecular Weight315.67
Melting Point139-141 °C
LogP4.6
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of EFAVIRENZ?

The CAS number of EFAVIRENZ is 154598-52-4.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of EFAVIRENZ?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy EFAVIRENZ or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

EFAVIRENZ · CAS 154598-52-4 · C14H9ClF3NO2. UNII JE6H2O27P8. Melting Point: 139-141 °C; Melting Point: 139 - 141 °C; Solubility: 8.55e-03 g/L.

Identification

CAS Registry Number154598-52-4
PubChem CID64139
Molecular formulaC14H9ClF3NO2
IUPAC name(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
UNII (FDA)JE6H2O27P8

Computed Descriptors

Molecular Weight315.67
XLogP34
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass315.0273907
Monoisotopic Mass315.0273907
Topological Polar Surface Area38.3
Heavy Atom Count21
Formal Charge0

Physical & Chemical Properties

Melting Point139-141 °C
Melting Point139 - 141 °C
Solubility8.55e-03 g/L
LogP4.6
Dissociation ConstantspKa = 10.2

Physical description & handling notes

  • Solid
  • Crystals from toluene:heptane
  • White to slightly pink crystalline powder
  • Practically insoluble in water (less than 10 mg/L)
  • 168.1 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID9046029]
  • Oral: Capsules: 50 mg, Sustiva, Bristol-Myers Squibb, 100 mg, Sustiva, Bristol-Myers Squibb, 200 mg, Sustiva, Bristol-Myers Squibb; Tablets: 600 mg, Sustiva, Bristol-Myers Squibb

GHS Hazard Classification

Reported hazard statementsH302 (52.3%), H319 (47.7%), H360 (48.9%), H372 (43.2%), H400 (92%), H410 (94.3%)

H302 (52.3%): Harmful if swallowed [Warning Acute toxicity, oral]

H319 (47.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Documented Uses

  • Anti-HIV Agents; Reverse Transcriptase Inhibitors
  • Use (kg; approx.) in Germany (2009): >1000
  • Use (kg; exact) in Germany (2009): 2025
  • Consumption (g per capita; approx.) in Germany (2009): 0.0122
  • Consumption (g per capita; exact) in Germany (2009): 0.0247
  • Consumption (g per capita) in the USA (2002): 0.0358

Synonyms

efavirenz; 154598-52-4; Sustiva; Stocrin; DMP-266; (-)-Efavirenz; (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one; (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; Viraday; Efavirenz teva; L-743726; Efavirenzum; DTXSID9046029; L-743,726; NSC-742403; JE6H2O27P8

Frequently Asked Questions

What are the CAS number and molecular formula of EFAVIRENZ?

CAS 154598-52-4; molecular formula C14H9ClF3NO2; molecular weight — g/mol.

What other names is EFAVIRENZ known by?

efavirenz, 154598-52-4, Sustiva, Stocrin, DMP-266, (-)-Efavirenz.

Is EFAVIRENZ classified as hazardous?

Hazard statements reported: H302, H319, H360, H372, H400.

What are the key physical properties of EFAVIRENZ?

Melting Point: 139-141 °C; Melting Point: 139 - 141 °C; Solubility: 8.55e-03 g/L; LogP: 4.6.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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