Enflurane

Description

Enflurane · CAS 13838-16-9 · C3H2ClF5O. UNII 91I69L5AY5. Boiling Point: 134 °F at 760 mmHg (NIOSH, 2024); Boiling Point: 56.5; Boiling Point: 56.5 °C.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Enflurane (Ethrane, 2-chloro-1,1,2-trifluoroethyldifluoromethyl ether) is a nonflammable halogenated hydrocarbon that exists as a clear, colorless, odorless to sweet, volatile liquid at ordinary temperature and pressure. Bp: 56.8 °C. Density 1.50 g cm-3 at room temperature. Used as an anesthetic.
• Clear, colorless liquid with a mild, sweet odor; inhalation anesthetic; [NIOSH]
• Liquid
• COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR.
• Clear, colorless liquid with a mild, sweet odor.
• Clear, colorless liquid with a mild, sweet odor. [inhalation anesthetic]

GHS Hazard Classification

Documented Uses

• Stable inhalation anesthetic; [ChemIDplus]
• Used for the induction and maintenance of general anaesthesia during surgery and cesarean section and also used for analgesia during vaginal delivery.
• Enflurane is prepared by dichlorination of the methyl group of 1-chloro-1,2,2-trifluoro-2- methoxyethane and replacement of these two chlorine atoms by fluorine.
• ... Prepared by successive chlorination and fluorination of the hydrocarbon ether.
• Prepn: Terrell, GB patent 1,138,406, US patent 3,469,011, US patent 3527813 (1969, 1969, 1970 all to Air Reduction)
• Fluorinated greenhouse gases (fluorinated GHGs) are man-made gases used in several sectors. They include hydrofluorocarbons (HFCs), perfluorocarbons (PFCs), sulfur hexafluoride (SF6), nitrogen trifluoride (NF3), and a number of fluorinated ethers. Fluorinated GHGs also include chlorofluorocarbons (CFCs) and hydrochlorofluorocarbons (HCFCs), but these ozone-depleting substances (ODSs) are currently being phased out and otherwise regulated under the Montreal Protocol and Title VI of the Clean Air Act, and EPA is not

Synonyms

enflurane; 13838-16-9; Methylflurether; 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane; Efrane; Ethrane; 2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; Alyrane; Compound 347; Anesthetic 347; Anesthetic Compound No. 347; OHIO 347; Enflurano; Ethane, 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-; Enfluranum; NSC-115944

Frequently Asked Questions

What are the CAS number and molecular formula of Enflurane?

CAS 13838-16-9; molecular formula C3H2ClF5O; molecular weight — g/mol.

What other names is Enflurane known by?

enflurane, 13838-16-9, Methylflurether, 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane, Efrane, Ethrane.

Is Enflurane classified as hazardous?

Hazard statements reported: H315, H319, H335, H332, H336.

What are the key physical properties of Enflurane?

Boiling Point: 134 °F at 760 mmHg (NIOSH, 2024); Boiling Point: 56.5; Boiling Point: 56.5 °C; Boiling Point: 56 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.