雌四醇

Description

ESTETROL · CAS 15183-37-6 · C18H24O4. UNII ENB39R14VF. Boiling Point: 491.9±45.0; Melting Point: 233-236; LogP: 2.62.

Identification

CAS Registry Number	15183-37-6
PubChem CID	27125
Molecular formula	C18H24O4
IUPAC name	(8R,9S,13S,14S,15R,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,15,16,17-tetrol
UNII (FDA)	ENB39R14VF

Computed Descriptors

Molecular Weight	304.4
XLogP3	1.5
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	0
Exact Mass	304.16745924
Monoisotopic Mass	304.16745924
Topological Polar Surface Area	80.9
Heavy Atom Count	22
Formal Charge	0

Physical & Chemical Properties

Boiling Point	491.9±45.0
Melting Point	233-236
LogP	2.62
Dissociation Constants	10.22±0.70

Physical description & handling notes

• Estetrol prevents pregnancy by suppressing ovulation.

GHS Hazard Classification

Reported hazard statements	H351 (75%), H360 (75%), H361 (25%), H362 (75%), H410 (50%)

Documented Uses

• Estetrol is indicated in combination with drospirenone for the prevention of pregnancy.
• Take with or without food. Take at the same time each day.
• Chemical Structure [CS] - Estradiol Congeners
• Established Pharmacologic Class [EPC] - Estrogen
• Mechanisms of Action [MoA] - Estrogen Receptor Agonists
• Estetrol anhydrous is an Estrogen. The mechanism of action of estetrol anhydrous is as an Estrogen Receptor Agonist.

Synonyms

ESTETROL; 15183-37-6; Estetrol anhydrous; 15alpha-hydroxyestriol; estetrolum; oestetrol; ENB39R14VF; Estetrol (anhydrous); 15 alpha-hydroxyestriol; estra-1,3,5(10)-triene-3,15alpha,16alpha,17beta-tetrol; CHEBI:142773; DTXSID50164888; Estra-1,3,5(10)-triene-3,15,16,17-tetrol, (15alpha,16alpha,17beta)-; 15 alpha Hydroxyestriol; RefChem:591228; 15 alpha Hydroxy Estriol

Frequently Asked Questions

What are the CAS number and molecular formula of ESTETROL?

CAS 15183-37-6; molecular formula C18H24O4; molecular weight — g/mol.

What other names is ESTETROL known by?

ESTETROL, 15183-37-6, Estetrol anhydrous, 15alpha-hydroxyestriol, estetrolum, oestetrol.

Is ESTETROL classified as hazardous?

Hazard statements reported: H351, H360, H361, H362, H410.

What are the key physical properties of ESTETROL?

Boiling Point: 491.9±45.0; Melting Point: 233-236; LogP: 2.62; Dissociation Constants: 10.22±0.70.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.