依他唑酯

Description

Etazolate · CAS 51022-77-6 · C14H19N5O2. UNII I89Y79062L.

Identification

CAS Registry Number	51022-77-6
PubChem CID	3277
Molecular formula	C14H19N5O2
IUPAC name	ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[3,4-b]pyridine-5-carboxylate
UNII (FDA)	I89Y79062L

Computed Descriptors

Molecular Weight	289.33
XLogP3	2.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	289.15387487
Monoisotopic Mass	289.15387487
Topological Polar Surface Area	81.4
Heavy Atom Count	21
Formal Charge	0

Documented Uses

• Investigated for use/treatment in alzheimer's disease and neurologic disorders.
• Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases.
• Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
• EHT 0202 was discovered to play a role in protecting neurons in pharmacological models of neuronal cell death. ExonHit identified RNA isoforms produced by alterations of splicing specifically taking place in neurodegenerative disease models. These isoforms were identified using DATAS(TM), ExonHit's proprietary gene profiling technology. DATAS(TM), stands for Differential Analysis of Transcripts with Alternative Splicing.

Synonyms

etazolate; 51022-77-6; Etazolato; Etazolatum; EHT-0202; I89Y79062L; 1H-Pyrazolo(3,4-b)pyridine-5-carboxylic acid, 1-ethyl-4-((1-methylethylidene)hydrazino)-, ethyl ester; DTXSID4048434; CHEBI:138502; ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[4,5-e]pyridine-5-carboxylate; ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo(4,5-e)pyridine-5-carboxylate; RefChem:137999; DTXCID0028408; Etazolate [INN]; ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[3,4-b]pyridine-5-carboxylate; ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate

Frequently Asked Questions

What are the CAS number and molecular formula of Etazolate?

CAS 51022-77-6; molecular formula C14H19N5O2; molecular weight — g/mol.

What other names is Etazolate known by?

etazolate, 51022-77-6, Etazolato, Etazolatum, EHT-0202, I89Y79062L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.