非洛地平

Name: 非洛地平
Brand: 济南圣和化工有限公司

CAS 72509-76-3C18H19Cl2NO4MW 384.2

非洛地平，CAS 登记号 72509-76-3，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于有机化学品。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号72509-76-3

分子式C18H19Cl2NO4

分子量384.2

熔点145

LogP3.86

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域有机化学品

类别有机化学品

用途与场景

有机化学品

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

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常见问题

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本页已列出非洛地平的 CAS 号：72509-76-3，可与随货 COA 核对。

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主要涉及有机化学品。

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PubChem 公开数据

Description

FELODIPINE · CAS 72509-76-3 · C18H19Cl2NO4. UNII OL961R6O2C. Melting Point: 145; Melting Point: 145 °C; Solubility: 19.7.

Identification

CAS Registry Number	72509-76-3
PubChem CID	3333
Molecular formula	C18H19Cl2NO4
IUPAC name	5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
UNII (FDA)	OL961R6O2C

Computed Descriptors

Molecular Weight	384.2
XLogP3	3.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Exact Mass	383.0691135
Monoisotopic Mass	383.0691135
Topological Polar Surface Area	64.6
Heavy Atom Count	25
Formal Charge	0

Physical & Chemical Properties

Melting Point	145
Melting Point	145 °C
Solubility	19.7
Solubility	7.15e-03 g/L
LogP	3.86
LogP	3.8
LogP	3.65

Physical description & handling notes

Solid

GHS Hazard Classification

Reported hazard statements	H302 (93.2%), H361 (22%), H373 (22%), H410 (15.3%)

H302 (93.2%): Harmful if swallowed [Warning Acute toxicity, oral]

H361 (22%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

Use (kg; approx.) in Germany (2009): >500
Consumption (g per capita; approx.) in Germany (2009): 0.00611
Consumption (g per capita) in the USA (2002): 0.00278
For the treatment of mild to moderate essential hypertension.
Felodipine belongs to the dihydropyridine class of calcium channel blockers (CCBs) and is approved by the United States Food and Drug Administration (FDA) for the management and treatment of essential hypertension.
Felodipine is a second generation calcium channel blocker and commonly used antihypertensive agent. Felodipine therapy has been associated with a low rate of serum enzyme elevations, but has not been convincingly linked to instances of clinically apparent, acute liver injury.

Synonyms

felodipine; 72509-76-3; Plendil; Flodil; Modip; Felodipina; Preslow; Felodipinum; DTXSID4023042; H 154/82; Felodipino; 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester; NSC-760343; OL961R6O2C; C08CA02; (+-)-Ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Frequently Asked Questions

What are the CAS number and molecular formula of FELODIPINE?

CAS 72509-76-3; molecular formula C18H19Cl2NO4; molecular weight — g/mol.

What other names is FELODIPINE known by?

felodipine, 72509-76-3, Plendil, Flodil, Modip, Felodipina.

Is FELODIPINE classified as hazardous?

Hazard statements reported: H302, H361, H373, H410.

What are the key physical properties of FELODIPINE?

Melting Point: 145; Melting Point: 145 °C; Solubility: 19.7; Solubility: 7.15e-03 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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