Ferrous gluconate

Description

Ferrous gluconate is identified by CAS 299-29-6, molecular formula C12H22FeO14 and molecular weight 446.04 g/mol. UNII 781E2AXH0K; InChIKey VRIVJOXICYMTAG-IYEMJOQQSA-L. Color Additive Status: 73.160; Color Additive Status: 184.1308.

Identification

CAS Registry Number	299-29-6
PubChem CID	23616740
Molecular formula	C12H22FeO14
Molecular weight	446.04 g/mol
IUPAC name	iron(2+);bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate)
InChIKey	VRIVJOXICYMTAG-IYEMJOQQSA-L
UNII (FDA)	781E2AXH0K

Computed Descriptors

Molecular Weight	446.14
Hydrogen Bond Donor Count	10
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	8
Exact Mass	446.035891
Monoisotopic Mass	446.035891
Topological Polar Surface Area	283
Heavy Atom Count	27
Formal Charge	0
Complexity	165

Physical & Chemical Properties

Color Additive Status	73.160
Color Additive Status	184.1308

Physical description & handling notes

• Pale greenish-yellow to yellowish-grey powder or granules, which may have a faint odour of burnt sugar
• The color of /ferrous gluconate/ solution depends on pH; they are light yellow at pH 2, brown at pH 4.5, and green at pH 7. The iron rapidly oxidizes at higher pH.
• The melting point for D-gluconic acid, ferrous salt dihydrate (98%) is 188 °C, decomposes. The specific optical rotation is +6.7 deg at 25 °C (c=1, H2O). /Dihydrate/
• Soluble with slight heating in water. Practically insoluble in ethanol
• Soluble in glycerin
• SOLUBILITY INCR BY ADDN OF CITRIC ACID OR CITRATE ION

Regulatory Status

Regulatory & Food Contact	FDA Regulatory Status of Color Additives: Foods FDA Substance added to food: COLOR OR COLORING ADJUNCT, NUTRIENT SUPPLEMENT COLOUR_RETENTION_AGENT; NUTRIENT_SUPPLEMENT: Food Additives Group PMTDI for iron, expressed as Fe TRS 759-JECFA 31/29 FAS 8/NMRS 55A-JECFA 19/26 (1975)
GHS notification summary	73.9% (17 / 23)

GHS Hazard Classification

GHS notification summary	73.9% (17 / 23)
Reported hazard statements	H302 (17.4%)

Documented Uses

• Nutrient or dietary supplement; trace mineral added to animal feed
• As coloring and flavoring in foods.
• For more Uses (Complete) data for FERROUS GLUCONATE (6 total), please visit the HSDB record page.
• Food Additives -> COLOUR_RETENTION_AGENT; NUTRIENT_SUPPLEMENT -> JECFA Functional Classes
• Prepared from barium gluconate and iron sulfate.
• By metathesis between hot solution of calcium gluconate and ferrous sulfate... . It may also be produced by heating ... ferrous carbonate with proper quantity of gluconic acid in aqeous solution. /Dihydrate/

Synonyms

FERROUS GLUCONATE; Ferroglyconicum; Glucoferron; Iron(II) Gluconate; Biofergate; Cerevon; Feravol; Ferlucon; Ferronicum; Ferrose; Glucomax; Gluferate; Nionate; Entron; Fenton; Ferox

Frequently Asked Questions

What are the CAS number and molecular formula of Ferrous gluconate?

CAS 299-29-6; molecular formula C12H22FeO14; molecular weight 446.04 g/mol.

What other names is Ferrous gluconate known by?

FERROUS GLUCONATE, Ferroglyconicum, Glucoferron, Iron(II) Gluconate, Biofergate, Cerevon.

What is the regulatory status of Ferrous gluconate?

Documented regulatory listings: FDA Regulatory Status of Color Additives: Foods; FDA Substance added to food: COLOR OR COLORING ADJUNCT, NUTRIENT SUPPLEMENT; COLOUR_RETENTION_AGENT; NUTRIENT_SUPPLEMENT: Food Additives.

Is Ferrous gluconate classified as hazardous?

73.9% of GHS notifications report no hazard classification (17 of 23).

What are the key physical properties of Ferrous gluconate?

Color Additive Status: 73.160; Color Additive Status: 184.1308.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.