马来酸非索罗定

Description

Fesoterodine maleate · CAS 286930-03-8 · C26H37NO3. UNII 621G617227.

Identification

CAS Registry Number	286930-03-8
PubChem CID	6918558
Molecular formula	C26H37NO3
IUPAC name	[2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl] 2-methylpropanoate
UNII (FDA)	621G617227

Computed Descriptors

Molecular Weight	411.6
XLogP3	5.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	11
Exact Mass	411.27734404
Monoisotopic Mass	411.27734404
Topological Polar Surface Area	49.8
Heavy Atom Count	30
Formal Charge	0

Physical description & handling notes

• Solid
• Highly soluble

GHS Hazard Classification

Reported hazard statements	H302 (100%), H315 (100%), H319 (100%), H335 (100%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >10
• Consumption (g per capita; approx.) in Germany (2009): 0.000122
• Fesoterodine is indicated for the treatment of overactive bladder in adult patients with symptoms of urge urinary incontinence, urgency, and frequency. It is also indicated in the treatment of neurogenic detrusor overactivity in pediatric patients ≥6 years old weighing >25 kg.
• Fesoterodine is an anticholinergic and antispasmotic agent used to treat urinary incontinence and overactive bladder syndrome. Fesoterodine has not been implicated in causing liver enzyme elevations or clinically apparent acute liver injury.
• Breast Feeding; Lactation; Muscarinic Antagonists; Parasympatholytics
• Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system.

Synonyms

Fesoterodine; 286930-02-7; Fesoterodina; [2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl] 2-methylpropanoate; 2-[(1R)-3-[bis(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl 2-methylpropanoate; DTXSID80182853; 621G617227; Propanoic acid, 2-methyl-, 2-((1R)-3-(bis(1-methylethyl)amino)-1-phenylpropyl)-4-(hydroxymethyl)phenyl ester; fesoterodinum; (2-((1R)-3-(di(propan-2-yl)amino)-1-phenylpropyl)-4-(hydroxymethyl)phenyl) 2-methylpropanoate; [2-[(1R)-3-(di(propan-2-yl)amino)-1-phenylpropyl]-4-(hydroxymethyl)phenyl] 2-methylpropanoate; 2-((1R)-3-(bis(propan-2-yl)amino)-1-phenylpropyl)-4-(hydroxymethyl)phenyl 2-methylpropanoate; RefChem:57404; DTXCID20105344; G04BD11; (R) Fesoterodine

Frequently Asked Questions

What are the CAS number and molecular formula of Fesoterodine maleate?

CAS 286930-03-8; molecular formula C26H37NO3; molecular weight — g/mol.

What other names is Fesoterodine maleate known by?

Fesoterodine, 286930-02-7, Fesoterodina, [2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl] 2-methylpropanoate, 2-[(1R)-3-[bis(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl 2-methylpropanoate, DTXSID80182853.

Is Fesoterodine maleate classified as hazardous?

Hazard statements reported: H302, H315, H319, H335.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.